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Vorinostat Group Buy - Fear Extinction and Learning and Memory enhancement

hdac inhibitor hdaci hdac fear extinction learning memory long-term memory vorinostat saha

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409 replies to this topic

#391 Infinite1

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Posted 15 January 2019 - 06:55 PM

One should be very careful about impugning on someone's honesty on a public forum without good reason. I ordered from him and it did take quite a few weeks, if not longer, to get the goods; considering it's the xmas period being referred to I would have thought that would be taken into consideration....

I certainly closed my business for nearly 2 weeks to have a well deserved holiday.

That wasn't my intention, although perhaps too hasty in posting given the holidays. Rather wished to let others know in the case things were no longer "up and running".  I am thankful for those that offer such service to the community, parallel too was my aim in posting as well.  

 

I do admit the second line was a bit farther than necessary, but thought it offered some humorous qualia. My apologies to SL 


Edited by Infinite1, 15 January 2019 - 07:06 PM.

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#392 Strangelove

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Posted 18 January 2019 - 06:58 PM

Hi Infinite1,

 

No everything is fine, it is my mistake, somehow I missed your post entirely, I sent your envelope adding one extra gram for the delay.

 

Sorry for the delays, replying to a few other messages, somehow the forum software got them on the bottom of the page and I just now saw them as well.


  • Cheerful x 1

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#393 jacobjerondin

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Posted 31 January 2019 - 02:50 AM

So it is necessary to feel fear, to unlearn it correct? Meaning if one was trying to use vorinostat to unlearn/make extinct fear of approaching and talking to girls at parties/bars, one should not be too drunk or other intoxicated on anxiolytics? So one should not take much or ideally anything that works on GABA with this stuff?

 

Also, according to this https://pubchem.ncbi...n-and-Excretion, Vorinostat is best absorbed with fat. That makes me think that it would be best absorbed sublingually, since as far as I know lipid soluble things are best absorbed that way? It should be absorbed better that way than it would be intranasally, is what I getting at, if my hypothesis is correct. I'd love to hear any input into this as this is just an educated guess on my part.


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#394 experimenting

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Posted 03 February 2019 - 07:53 PM

OK so,

 

Lots of users, but few long-term and detailed experience reports.

 

First off, I'm curious as to the nature of fear extinction. Some have posited that it's a creation of new "anti-fear" memories, if you will; others say it's an erasure of fear; still others argue that both are possible. If both are possible, which category does Vorinostat fit in?

 

For those who have used it medium-term: are the effects permanent? Prior fears are gone, and do not return even after cessation of use? 

 

Also, if one extinguishes one's fears, there are likely downstream personality effects (especially if the erasure hypothesis is true). What have people noticed in this regard? Improved learning ability? More wonder at the world?

 

I feel that this is a VERY promising substance but that the info thus far isn't quite so detailed. Just trying to get the conversation going.

 

 

Thanks!

 

 

 


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#395 experimenting

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Posted 05 February 2019 - 04:10 AM

Bump
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#396 experimenting

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Posted 06 February 2019 - 12:16 AM

Hi Infinite1,

No everything is fine, it is my mistake, somehow I missed your post entirely, I sent your envelope adding one extra gram for the delay.

Sorry for the delays, replying to a few other messages, somehow the forum software got them on the bottom of the page and I just now saw them as well.


Strangelove, you around?
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#397 Mycarflies69

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Posted 07 February 2019 - 05:41 PM

Looking for Strangelove also!!!  



#398 theobromananda

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Posted 09 February 2019 - 11:57 AM

Any ideas on rectal use of a SAHA infusion? It might be a good way to change the epigenetic status of the gut.



#399 experimenting

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Posted 12 February 2019 - 09:13 PM

Bump
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#400 Strangelove

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Posted 16 February 2019 - 09:21 PM

Hi everyone, 

 

Yes, I am still here, I will be shipping the last 4 X 2-gram envelopes and that's it, unfortunately, the contact that helped me get Vorinostat cannot help me anymore.



#401 experimenting

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Posted 16 February 2019 - 09:42 PM

Hi everyone,

Yes, I am still here, I will be shipping the last 4 X 2-gram envelopes and that's it, unfortunately, the contact that helped me get Vorinostat cannot help me anymore.


I’ll take all 4, pm please.

#402 Mycarflies69

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Posted 17 February 2019 - 05:07 AM

Hi everyone,

Yes, I am still here, I will be shipping the last 4 X 2-gram envelopes and that's it, unfortunately, the contact that helped me get Vorinostat cannot help me anymore.


I’ll take all 8 grams and outbid
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#403 experimenting

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Posted 17 February 2019 - 02:05 PM

I’ll take all 8 grams and outbid


Surely we can find a way this works for both of us, 4g each?
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#404 Mycarflies69

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Posted 17 February 2019 - 07:30 PM

Surely we can find a way this works for both of us, 4g each?


I mean I guess........ /teardrop
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#405 Mycarflies69

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Posted 18 February 2019 - 07:16 PM

Tried two sessions, one at 100mg and one at the 150mg. I have severe social anxiety and I have a group therapy class which I go to , in the class we do exercises that increase our level of fear and basically have to work through it forcefully exposure therapy like. Can’t say I feel a difference in my every life maybe a little improvement nothing drastic. I also go in with 30-40mg propranolol and. 2mg of Xanax. Debating if I should stop the Xanax or if it has anything to do with it. Also on Tianeptine 12.5mg x 3 a day.

Edited by Mycarflies69, 18 February 2019 - 07:17 PM.


#406 experimenting

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Posted 18 February 2019 - 08:54 PM

Tried two sessions, one at 100mg and one at the 150mg. I have severe social anxiety and I have a group therapy class which I go to , in the class we do exercises that increase our level of fear and basically have to work through it forcefully exposure therapy like. Can’t say I feel a difference in my every life maybe a little improvement nothing drastic. I also go in with 30-40mg propranolol and. 2mg of Xanax. Debating if I should stop the Xanax or if it has anything to do with it. Also on Tianeptine 12.5mg x 3 a day.


Ugh. I really was hoping this would be a game changer. Not worth it?
  • Enjoying the show x 1

#407 Mycarflies69

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Posted 19 February 2019 - 11:03 PM

Well I have two grams of this stuff from a confirmed source , I am hoping that the vorinostat aids in my social anxiety but I don’t feel any acute effects one hour after ingesting or anything psychological effects really. The propranolol is what really helps me with my social anxiety and general anxiety. It’s better than benzodiazepines cause you can learn to work through your anxiety rather than being a zombie.
  • Enjoying the show x 1

#408 theobromananda

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Posted 20 February 2019 - 04:33 PM

https://sci-hub.tw/10.1111/nmo.12675
https://sci-hub.tw/1...arm.2016.03.012
https://sci-hub.tw/1...ci.1758-09.2009

https://sci-hub.tw/10.1038/nrn2749

https://sci-hub.tw/1...pbp.2015.03.010

https://www.ncbi.nlm...pubmed/29452193



#409 Infinite1

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Posted 20 February 2019 - 05:36 PM

Hi Infinite1,

 

No everything is fine, it is my mistake, somehow I missed your post entirely, I sent your envelope adding one extra gram for the delay.

 

Sorry for the delays, replying to a few other messages, somehow the forum software got them on the bottom of the page and I just now saw them as well.

Looking forward to receiving this...Do you have tracking on it? 



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#410 doctordron

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Posted 22 February 2019 - 08:16 PM

Is anyone here or somewhere to provide new group buy ? Or anyone who knows actual sources . ?







Also tagged with one or more of these keywords: hdac inhibitor, hdaci, hdac, fear extinction, learning, memory, long-term memory, vorinostat, saha

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