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Anti-depressant induced HYPO-pigmentation?

sertraline mirtazapine vitiligo pigmentation medication-induced

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#1 Mind_Paralysis

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Posted 29 May 2017 - 01:50 PM


Not sure where to post this, but since it included AD's, I decided to post it here - Moderators feel free to move if in the wrong section.

 

Yeah, I have a close relative who has been on Sertraline for some time, on and off (she's bad at taking it consistently - oddly enough she doesn't get any discontinuation-symptoms, unlike myself) and last year she complained about pigmentation-loss, which eventually got better.

 

However, recently, with the return of spring, and when starting up Sertraline again as well, the white spots and hence loss of pigmentation returned - she's had several blood-tests which did not show anything off with her TSH or T4 - although it DID show that she is slightly anemic, with a too low blood-count (around 26, I believe, I myself have a value of 46) - even though she is also a smoker, which is supposed to increase your Hb-value, but apparently not in her case.

 

But could the loss of pigmentation be connected to Sertraline? The fact that it flared right back up when she started using it again, certainly speaks towards this. HOWever... when checking the documentation and online reports, all I see are cases of HYPER-pigmentation! Not hypo. That certainly seems to fly straight into the face of her own, and my, suspicions of Sertraline causing it.

She also uses Mirtazapine, but very rarely, as she does not like the weight-gain effect, nor the complete anti-histamine hangover which seems to hit her almost as badly as it hits me.

 

 

Could the loss of pigmentation be connected to her diet, by chance? She has some symptoms of arthritis as well, and reading up on it, I see that arthritis and vitiligo seems to be connected somewhat, perhaps sharing some common auto-immune disruption mechanism.

 

Any ideas, gentle-folks?

 

 

EDIT:

D'oh! Just found tons of evidence that vitamin deficiencies can lead to loss of pigmentation - bloody skurvy, ahoy, my mates!

 

http://www.livestron...mentation-loss/

 

Hmm... she needs to eat better.

 

I can't recall exactly if they tested her B12 levels and what they were, but I believe they did, and they were within normal ranges. However, as I understand it, Vit C and B9 are also important for pigmentation.


Edited by Stinkorninjor, 29 May 2017 - 01:56 PM.






Also tagged with one or more of these keywords: sertraline, mirtazapine, vitiligo, pigmentation, medication-induced

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