187 replies to this topic

[thefirstimmortal]

Hello
The Cognitex formula is a mild Nootropic formula (It contains 1 strong (Vinpocetine) and 2 weak (Alpha GPC & PS) Nootropics). I have taken this product since it came out and have notice some mild results. I don't recommend the product as a stand alone for the serious Life Extensionist or for it to represent the more potent  Nootropics. [Deprenyl, Piracetam, Pyritinol, Hydergine, and Idebenone are good examples.

Do you recall when Cognitex came out?

[bugmenot.com]

Has anyone done a price comparison on Huperzine A? Found a good and inexpensive supplier? I used to purchase it at Puritan's Pride (at what I thought was a very good price) but they no longer carry it.

TIA

[thefirstimmortal]

Are any of you here paying any attention to the free speech forum debate. You might want to start.

I have left Immortalurnot signatures' intact for his *speech*  and systematically disabled his links to sites that *market*

based on this, you guys might lose all your links.

[thefirstimmortal]

So in the name of...whatever you're going to inconvenience everyone in this forum or anyone who might seek this reference thread?

Metaphorical me thinks.

Who, me. [huh] Naw, me thinks it's a real bad Idea, but check out the full members forum under "Don Spanton on banned products". Also, you might want to check out " Amendments being proposed to the Free Speech Forum Censorship of "free speech". It could end up changing your forum also. Do you like your links? I hope so, be prepared to fight for your right to keep em'.

[nootropi]

"Don Spanton on banned products"

Why am I not surprised. 

It is interesting that on the Avant board--a board sponsored by a supplement company one can say almost anything, including that their products are terrible (as long as you give some reasonable justification), but here censorship rears its ugly head.  Of course censorship in the name of what is right....an old pattern....

No offense, Scott, but it is not censorship to delete garbage from our view. It is only to respect our eyes' limited view and shortage of time. If somebody is overzealous on any issue, and is posting absolute garbage I would only think it rational to move it to another category, perhaps "garbage?" Do you think we could benefit from such a subcategory? You (hopefully) would not find me posting there at all...

In my humble opinon, the Avant labs forum has a lot of garbage too. A bit too much for my eyes (just a bit; some members I think are really sharp. Some are on too many prohormones, which has a detrimental effect on their logic). If I spend too much time in that dark forum my eyes grow weary and I long for the tranquil blue imminst forum...ahh... heaven... [thumb]

[nootropi]

Hey scottl,

I am not sure exactly what you are getting at; I just hope that this forum does not digress into debates which are really counterproductive. Members do benefit from the knowlege of other members, which should not be discounted.

[nootropi]

I would just like to say that I did not read whatever remarks were removed. I just know that Bruce, one of the most outspoken free speech folks around here, would only remove posts that were either unnecessary or unpleasant. He encourages debates (rational ones, that is). But you see, this very thread has digressed from the topic "Nootropic Sources Listings:" so please keep in mind that some viewers might not get to read the sources on the previous pages if we keep up this digression here.

[jpars82]

New Piracetam source

I just added a new Piracetam source. Their price is pretty good at 120caps/$19.50... it comes from Colorado Nutrition. They also have a really good deal on ALA and ALCAR plus some pretty potent Rhodiola.

Note: I have not tested/tried any of their products myself yet though. But if anyone wants to give 'em a shot let us know.

Josh

[hondoleroy]

Have tried ordering through web site of Smi2le.biz several times over the last two - three days, with no luck.

When the ordering page finally does load up, it gets a "Server Error Message"

*************************************************************
Server Error in '/smi2le' Application.
--------------------------------------------------------------------------------

Runtime Error
Description: An application error occurred on the server. The current custom error settings for this application prevent the details of the application error from being viewed remotely (for security reasons). It could, however, be viewed by browsers running on the local server machine.

Details: To enable the details of this specific error message to be viewable on remote machines, please create a tag within a "web.config" configuration file located in the root directory of the current web application. This tag should then have its "mode" attribute set to "Off".

*************************************************************

I am kind of new to this game and SMI2Le seemed like a very excellent source for my needs (high cortisol problems along with moderate to severe anxiety and mild to moderate depression).

Anyone have any information with what is currently going on there? Web site problems? Business organization problems?

Any information would be appreciated!

Hondo

[nootropi]

Have tried ordering through web site of Smi2le.biz several times over the last two - three days, with no luck.

When the ordering page finally does load up, it gets a "Server Error Message"

*************************************************************
Server Error in '/smi2le' Application.
--------------------------------------------------------------------------------

Runtime Error
Description: An application error occurred on the server. The current custom error settings for this application prevent the details of the application error from being viewed remotely (for security reasons). It could, however, be viewed by browsers running on the local server machine.

Details: To enable the details of this specific error message to be viewable on remote machines, please create a tag within a "web.config" configuration file located in the root directory of the current web application. This tag should then have its "mode" attribute set to "Off".

*************************************************************

I am kind of new to this game and SMI2Le seemed like a very excellent source for my needs (high cortisol problems along with moderate to severe anxiety and mild to moderate depression).

Anyone have any information with what is currently going on there? Web site problems? Business organization problems?

Any information would be appreciated!

Hondo

To contact smi2le.biz try calling: (USA) 856-652-9118. Ask for Mike; if you get one of the secretaries, they should be able to help you too. But to get special items, or to assay products, you need to ask to speak directly with Mike.

Check out the assays I have conducted of his products:

I am an independent consumer in this market. I have tested several of the products that are sold by smi2le.biz, in exchange for store credit. The products that are sold at 1fast400 or beyond-a-century.com are not tested by an independent third party; therefore you are making the gamble that these products are safe when imported from countries, such as China and India. If you feel comfortable taking large doses of substances from an unregualted market, that is your choice.



Please consider the results of the assays of products from smi2le.biz after considering these definitions:


USP <231> Heavy Metals

The limit test for heavy metals is a qualitative test that demonstrates that the content of metallic impurities that are colored by sulfide ion does not exceed the specified limit.  Metals that typically respond to this test are lead, mercury, bismuth, arsenic, antimony, tin, cadmium, silver, copper, and molybdenum.

Melting point

The melting point is used in chemistry as a rough guide to purity, since a pure crystalline compound will generally melt over a range of a few degrees, and is depressed by impurities (or polymorphs). Liquefaction, and in many cases subsequent recrystallisation upon cooling follows melting. In the case of RLA, the material actually polymerizes below its melting point and you see no changes upon heating all the way up to 250 deg C, where the material begins burning. The only way to get a usable melting point is to have a device pre-set to 49 deg C, place a sample on a microscope cover slip and to drop it on the pre-heated surface. Even then you get polymerization in many cases rather than a clean melt even though the material is pure by HPLC. This is why we don’t use the melting point has the sole criteria of purity. 

Click here for source


1. Smi2le.biz's idebenone; test conducted for melting point (54-55); moisture/loss on drying (0.519); satisfies USP specification for heavy metals at <0.05 parts per million (so the sample satisfies USP specification at less than 10 parts per million of lead, mercury, bismuth, arsenic, antimony, tin, cadmium, silver, copper, and molybdenum);



[original image: http://www.imminst.o...-1101051678.jpg]

2. Aniracetam from smi2le.biz; test conducted for purity (98.11% pure; but don't forget to add the moisture level as well as moisture/loss on drying to the sample's integrity level);


[original image: http://www.imminst.o...-1101913520.jpg]


3. L-carnosine from Smi2le.biz; tested for melting point at 250 degrees celcius (which enables us to identify the substance by measuring the temperature at which a supplement dissolves) as well as heavy metals (satisfies USP specification at less than 10 parts per million of lead, mercury, bismuth, arsenic, antimony, tin, cadmium, silver, copper, and molybdenum);


[original image: http://forum.avantla...-1104544712.jpg]

To read more about the benefits of L-carnosine supplementation: click here

4. Oxiracetam from Smi2le.biz tested for tested for melting point tested at 168 degrees celcius (which enables us to identify the substance by measuring the temperature at which a supplement dissolves) as well as USP metal assay (satisfies USP specification at less than 10 parts per million of lead, mercury, bismuth, arsenic, antimony, tin, cadmium, silver, copper, and molybdenum);



[original image: http://www.imminst.o...-1104542557.jpg]

To learn more about oxiracetam and its benefits, Click here.

5. Pyritinol from smi2le.biz tested for melting point to 138 degrees celcius (which enables us to identify the substance by measuring the temperature at which a supplement dissolves) as well as heavy metals: lead, mercury, bismuth, arsenic, antimony, tin, cadmium, silver, copper, and molybdenum):


[original image: http://www.imminst.o...-1104542962.jpg]

To read more about the benefits, suggested dosages and the respective medical abstracts, simply click here.

To read earlier correspondences: click here and here

Edited by nootropi, 10 January 2005 - 01:41 AM.

[lemon]

Hydergine at Biogenesis are not FAS. Both Nootropi and I have ordered them.

[sja_]

customnutritionwarehouse will be carrying some Nootropics very soon. He is usually very reasonably priced with his other products so I can't wait to see what comes of his new stock.

[vortexentity]

Looks like he is already. I was looking for a source for Phosphadityl-Serine bulk powder and it looks like he has it in stock. thanks

[psychenaut]

A site with a very wide selection of products from Life Extension and Advanced Orthomolecular Research is Relentless Improvement.

For the money and simplicity, AOR's combo product Ortho-Mind is tough to beat. Ingredients include:
180 caps total Serving Size: 6 Capsules %DRI
R(+)-lipoic acid ……………………................. 100 mg *
Huperzine-A (from 20 mg Huperzia serrata 0.5%) 100 mcg *
Vinpocetine ……………..……………. 15 mg *
Bacopa monniera extract(50% baccosides A&B) 300 mg *
Ginkgo biloba extract……………….. 100 mg *
(24% ginkgoflavone glycosides, 6% terpene lactones)
Cytidine diphosphate choline (CDP-Citicoline) ……….. 500 mg *
Acetyl-L-Carnitine HCl (ALCAR)…………………. 1500 mg *
L-Pyroglutamic Acid (base 'racetam molecule) ………………….... 1500 mg *
Pantothenic acid ………………….... 500 mg 10000%

The beauty of the Ortho-Mind formula is its synergistic combo of ingredients, designed not just to enhance but also protect. AOR's pharmaceutical quality and attention to dosages make this an easy supplement to have complete confidence in. If you calculate the expense of the ingredients purchased separate, it is also tough to beat Ortho-Mind from a price standpoint.

Also a great combo is Life Extension's
Cognitex which could certainly be considered a brain booster:

Serving Size 3 softgels
Servings Per Container 30
Amount Per Serving
L-alpha-Glycerylphosphorylcholine (Alpha GPC) 600 mg
Nexrutine® 500 mg
Water-soluble quercetin 125 mg
Phosphatidylserine 100 mg
5-Loxin 50 mg
Pregnenolone 50 mg
Vinpocetine 15 mg

A person (with a bigger budget) seeking maximum effect, might add to the Cognitex, LEF's Mitochondrial Energy Optimizer with SODzyme which contains an additional array of cognitive enhancers including patented ALCA-Arginate:

Serving Size 4 capsules
Servings Per Container 30
Amount Per Serving
Thiamin (vitamin B1) (as thiamine HCl) 50 mg
Acetyl-l-carnitine hydrochloride 750 mg
Acetyl-l-carnitine arginate dihydrochloride 750 mg
Carnosine 1000 mg
SODzyme Proprietary Phytoenzyme Blend (Glycine max, zea mays, wheat sprout concentrate) 300 mg
Benfotiamine 150 mg
Luteolin [from Perilla leaf extract (Perilla frutescens)] 8 mg
R-lipoic acid (as potassium-R-lipoate) 150 mg
Rhodiola rosea root extract [standardized for 3% Rosavins (4.5 mg) and 1% Salidrosides (1.5 mg)] 150 mg

Life Extension is quite well regarded for its pharmaceutical quality and intelligent dosing. Once again when considered against the expense of ingredients purchased separate and the hassle factor of taking all the different pills/powders/liquids and figuring out dosages, it makes a strong case for a combo-product.

Like car enthusiasts, we all like to consider getting under the hood to tinker just a bit, and build our own hot-rod from scratch. But we all also realize that for 99% of us it is tough to improve on an expertly pre-constructed, well-engineed Corvette or Ferrari.

Relentless Improvement ships from the USA, immediately confirms all orders by email and emails a USPS tracking number. Orders over $100 have free S&H. Why order LEF from us? You save an $80 membership fee and you always get member pricing (or better). Because of our strong relationship with Life Extension Foundation, we are the only distributor they actually link to from their Site. Support three great companies that support the life extension community.

Kind Regards,
psychenaut

[ozone]

@psychenaut
I really don't think the Ortho-Mind is that great of a deal in all honesty. I mean, it apparantly only contains about 80-40mg of RALA, and according to AORSupport with 1.5g of ALCAR you're going to want at least 689mg-1.5g of KRALA (depending on the content of RALA). So if you're taking Ortho-Mind, you'll need more RALA than that.

@LifeMirage
Why don't I ever see you guys supporting SHF's store? Apparanlty they have really great stuff, and a lot more reliable than other folks... http://www.shfnatura...mvc?Screen=SFNT

[psychenaut]

ozone-

Thanks for your post.

Not sure where you got 80-40mg R(+) from, but as previously posted the correct R(+)-Lipoic Acid content per serving size, and per the 1500mg ALCAR that you chose to compare it to-
R(+)-lipoic acid ……………………................. 100 mg *
You are correct, it is a great idea to supplement with additional R(+)-Lipoic Acid. I personally choose to do so using AOR's R(+).

After doing a forum search I cannot find the post which substantiates what you claim AORsupport said-

ozone-
with 1.5g of ALCAR you're going to want at least 689mg-1.5g of KRALA

However a relevant AORsupport quote would be, and I would point out that R(+) is what is discussed, not KRALA-

AOR-
Based on the Hagen/Ames studies, an appropriate dose after adjusting for allometric metabolic scaling would be 1.29 to 4.3 g of ALCAR and 612.6 - 1225.2 mg R-Lipoic.

Now let me address your ALCAR/R(+) ratio question, which is right on target. AORsupport has previously posted-

AOR- "To be clear, this ratio [more R(+)] is ideal from a dosing perspective, but to combine this much RLA with ALCAR and nothing else in one tablet draws in a lot of moisture [because it is hygroscopic], greatly increasing polymerization [bad].

In their animal studies, Hagen and Ames solved this problem by administering RLA and ALCAR separately despite the inconvenience [truncated]

AOR has avoided this by not producing such a product -- yet. It is for this reason that AOR encourages the use of a separate ALCAR supplement to complement our RLA-only product, and a separate "top-up" RLA supplement for Ortho-Mind, whose RLA content is otherwise suboptimal."

I hope this clears some questions, and I am glad that you posted so that I might better understand this important issue myself. Advanced Orthomolecular Research's integrity has proven time and again to be unassailable. Their formulations are always well thought out, much more so than any other supplier we know. That is why we are proud to represent their product on our site RelentlessImprovement.com

AOR is committed to the life-extension cause, and along with Life Extension Foundation are top contributors and supporters of the Methuselah Mouse prize. These are companies that I want to support with my business.

Going back to the car analogy I used in my previous post, that new Corvette (Ortho-Mind) you bought might be safer on the racetrack with a roll cage (more R+), and faster with racing slicks (more ALCAR), but the basic well engineered platform (pharmaceutical quality) is there for those that choose to tweak it.

Kind Regards,
psychenaut

Edited by psychenaut, 24 March 2005 - 09:02 PM.

[ozone]

@psychenaut

Ahh, sorry about the KRALA confusion. But the numbers for that are correct if dealing with KRALA from Genovia (or whatever that place is called). Their KRALA is 40% RALA, so for 1.5g of ALCAR you'd want 1.5g of KRALA. Again, not really important if you are going to be taking RALA.

Also, I now remember from a document I was reading last night that RALA has that problem in regards to mixing it with ALCAR in a cap. That's why I'm focusing on KRALA since it can be mixed with ALCAR. Unfortunately, it's fricking expensive hah. Oh well.

[ozone]

LifeMirage
Why don't I ever see you guys supporting SHF's store? Apparanlty they have really great stuff, and a lot more reliable than other folks...

QUOTE
These Listings are for Nootropic Suppliers SHF it a bulk supplements supplier. As far as nootropics go they have little of interest.


Acetyl-L-Carnitine, powder, 500g $50
Ascorbic Acid, (Vitamin C), USP, fine powder 500g $20
Bacopa monniera extract, (20% standardized for bacosides), powder, 500g $50
Citicoline (CDP-choline), powder, 100g $95 "This is the only store on the internet I've found that sells CDP bulk powder"
Ginkgo biloba extract (24% Ginkgoflavoglycosides/6% terpenes standardization), powder 100g $25
Ginseng extract (8% ginsenosides standardized), powder 500g $35

I especially like the CDP.

Edited by BJKlein, 07 April 2005 - 09:58 AM.

[ozone]

Hey lifemirage, when you said DNPINT, did you mean that SHFnatural uses DNPINT to supply Citicoline (CDP-Choline)? If not, were you referring to buying from DNPINT directly? And if so, what is the price you were quoted on a kg of CDP?

[ozone]

Just a followup. I ordered from SHFNatural.com and got my stuff today. It was sent priority and it's top notch. It all came with assays and professionaly sealed in double-zip bags. If anyone wants snapshots of what I got just ask (I won't be capping them for a few days).

[ozone]

Hey lifemirage, I was reading what UNI said about their piracetam. It's from DNPINT but from China. This makes me wonder if everything www.dnpint.com sells is from China. The sole purpose for asking is again, I like to know what I ingest. I was talking about who I recently got my order from SHFNatural and each pack of powder had an assay printout. Funny thing way, on the bottom of the page were the words "This assay was provided to us by our supplier." It didn't say who the supplier was, but I guess trying to find the source of something isn't as easy as it seems.

But anyway, any info you have on DNPINT would be helpful. Thanks.

[jolly]

FYI,
Anti-Aging-Drugs.com just e-mailed me saying they have a sale going on with 20-25% off untill May 1st. They dont have the best selection, but they do have nice prices for Deprenyl.

SELEGILINE - JUMEX
Jumex - 50x5mg - $34
Jumex - 150x5mg - $97
Jumex - 30x10mg - $34
Jumex - 60x10mg - $62

SELEGILINE - GENERIC
Selegiline 100x5mg - $55

http://www.anti-agin...kinsonism#jumex

[matpal]

As posted elsewhere, I now have Sulbutiamine.

http://customnutriti...b56bbfb590a24a7

[haveblue]

Its not in pounds, its in Euros.

26.50 Euro = 34.07 USD

[exigentsky]

Where can I buy high quality relatively inexpensive Alpha-GPC?

[exigentsky]

Yes, but theirs is out of stock and I have an allergic reaction to back orders.

[lemon]

I wanna buy Alpha-GPC directly from the manufacturer like I do for Sigma Tau and Geronova.

[seeker]

Ordered from CNW and Biogenesis around the end of April. CNW was delivered within three days and Biogenesis within about 10. Highly recommend both!