Have a history of panic and anxiety issues. Recently tested for SNP's and am homozogous for MTRR A66G +/+ and COMT H62H. Started on Adeno B12, B6 (P5P) and feel good. In fact P5P 20 mg seems to reduce my tinnitus, maybe it helps reduce brain inflammation.
The biggest problem seems to be the anxiety. It appears that I am may be estrogen dominant as I feel more anxious on Turmeric, Catechins, EGCG, Fish oil etc...Hair Mineral Test indicated that I may have bio unavailable copper in the body. Copper and Zinc in serum are in the normal range.
I am looking for COMT enhancer and also something that can reduce copper and estrogen in my body (testesterone is low). I know Turmeric reduces estrogen but that also inhibits COMT and that causes me more anxiety. Also have hyper pigmentation patches on the forehead and cheeks which may be caused due to copper toxicity(?).
I am trying to solve the anxiety puzzle and any help would be greatly appreciated?
Thanks
