7 replies to this topic

[leclochard]

Hey all,

I'm thinking about starting an intesive regimen with the following goals:

GOALS:

- Improving my general health (so also to increase my resistance)
- To fight aging
- To prevent diseases
- to get more energy
- To reduce stress and anxiety
- And if it's possible, to lower the effect of allergies (hayfever, asthma)

I want to become old in a very healthy and (preferably) good looking way, while having tons of energy to fulfill my life goals.

I have made a list of supplement for myself. Money is not really an issue, but still I don't want to spend more than 150 dollar per month. I do want to shorten the list a bit though, because I'm sure some things will be double and I only want the BEST quality. It should be the BEST package I can make for myself.

1 | I have to make a selection out of this list (I cannot take them all I think) and I want to know if some supplements cancel out each others effects? I.e. do all these supplements mix well, or should I avoid taking some of them at the same time? It could lose its effect, or the effects of taking some supplements at the same time could even be harmful.

2 | Which are defenitely the best ones? (price/quality relation).

3 | I would also like to know if some supplements might be redundant, taking into account some supplements offer the same health boosts. I can imagine it is useless taking 10 different types of strong anti-oxidants with the same effect for example. In that case I would only like to take the best one(s).

This is the list I have made, with behind the supplement the qualities scientists assigned to them:

• Pterostilbene (anti-aging, cancer prevention, lowers blood pressure)
• Xantahumol (cancer prevention, diabetis prevention)
• Resveratrol- 50mg (longevity, mental boost, disease prevention)
• L-Carnosine (Supports longevity, Delivers wide-ranging antioxidant protection and supports enzyme systems)
• Acai Berry Extract (high potency antioxidant formula that helps increase vitality and combat free radicals)
• NAC-L/Cysteine (free radical fighter, very powerful anti-oxidant. Boosts liver healthiness)
• Pomegranate Extract (Promotes proper liver and cardiovascular system maintenance, strengthening immune system, strong anti-oxidant)
• Spirulina (Delivers powerful antioxidant support, potent joint health and more)
• Weed Grass (Energizing, whole-food nutrition)
• Broccoli Extract Sulforaphane (Fights free radicals with broccoli's active ingredient)
• Cinamon (Promotes blood sugar health already within a normal range)
• Chlorella (Features a comprehensive blend of vitamins, minerals, amino acids and antioxidants)
• Methylcobalamin B-12 (makes a difference in the health of the peripheral nerves, boost of energy, boost for mental functions )
• Coconut Oil (From what I have heard a wonderful ingredient to cook with, to apply on your and on your hair)
• Ashwagandha (to reduce stress, reduce anxiety, build muscle and promote relaxation)
• Rhodiola (against anxiety and to reduce stress)
• Schizandra (against anxiety and to reduce stress)
• Lysine-one (against anxiety and to reduce stress)
• Bacopa (For memory enhancement)
• White tea (good for general health and mental boost)
• Green Tea Extract (good for general health and mental boost)
• Acetyl-L-Carnitine (Provides antioxidant protection throughout the nervous system, passes through the blood-brain barrier to support cognitive health & optimal brain function, improves concentration and support memory)
• Vitamine D3 (The sunshine vitamin. Supports bone, immune, emotional health and more and support happiness)
• Curcumin (Promotes proper liver and cardiovascular system maintenance, strengthening immune system, strong anti-oxidant)
• Omega 3 (Ultra) (Support cardiovascular health and overall wellness)
• Ubiquinol (Boosts energy levels and overall health, inhibits inflammation) (more important when I become older though)
• Multivitamin (What is the best brand? Ultimate Dialy Support?) (For general health)
• Garlic Extract (Aids cardiovascular and immune system function)
• Alpha Lipoic Acid (Ultra-potent support for healthy glucose metabolism, possesses quality antioxidant properties that rejuvenate other antioxidants)
• Magnesium (to reduce stress and insomnia, to reduce anxiety)
• Country Life calcium magnesium complex (For my general magnesium and calcium level, may substitute the magnesium supplement. For general health)
• Zinc (for increased testosterone production (+ acne drug))
• Selenium (Promotes heart and prostate health, is also a good way to shore up your body's antioxidant defenses)
• Silver (Helps the immune system defend the body)
• Boron (Against prostate cancer and good for the bones)
• Probiotics (for a general strong immune system boost_
• Maca (for increased libido)
• Tribulus Terrestris Extract (for increased performance (sports, especially heavy weight lifting) + increased libido)
• Whey Protein (Enhances your workouts by providing terrific muscle nutrition, improves recuperation)
• Inneov Solaire Intesif (For skin protection against the sun during the summer months)

Like said before, some supplements seem to boost the same stuff. I suppose a lot of them are redudant and I can make a very good regimen with maybe 15 of these supplements). I will leave it up to the experts here though, if the best regimen would entail a set of supplements costing 200 dollars, I will accept that.

If you could also elaborate/motivate your selection, I would be delighted

I thank you in advance for your help! For a healthy and peaceful future!

Cheers,

leclochard

[Andey]

Hi
Are you in 40+ period of your life ?
I ask because I wouldnt take majority of supplements here if I would be in my twenties )
Also dosage make a difference.

You lack of two most promising longevity supplements - C60 and metformin. They didnt studied well but safety profile is very good and so far it looks that you could achive more effect with them then with whole your regiment combined. C60 works with antioxidant part of aging, metformin with glycation part.

For the rest of supplement - I honestly didnt know much about majority of them but I personally use Rhodiola(good), Ashwagandha(could not recomend because didnt feel how it works)
Must have supplements: Curcumin, Milk Thistle(both are not so bioavalable so I prefer binded with soy), Magnesium, Melatonin (low dosage or TR), Vitamin D3
Antiglycation - metformin (I started low dosage TR time release type), Cinnamon or Green Cofee before large meals, Carnosine but I dont sure about biovalability aspect
Cardivascular - I think about to add Pomegranade extract to my regimen and thats it, regular excercise do the rest.... and Vit K + K2
Antioxidants: C60 and may be NAC (there are some synergy reported between them), may be some vit C and low dosage of Alpha Lipoic acid as neuroprotective and chelating agent.

Dont forget that supplements regimen is not all - good diet and regular excercise even more important.

Edited by Andey, 12 May 2013 - 08:36 AM.

[DorianGrey]

My 2 cents, maybe it helps you prioritize. Going through your list gave me a good opportunity to check for gaps in my own stack.

• Resveratrol- 50mg (longevity, mental boost, disease prevention) --> I drink red wine and berry or grape juices, but I wouldn't supplement Resveratrol. There's talk it may inhibit telomerase at higher doses. Maybe once I have a health issues like a tumor I'll reconsider.
• L-Carnosine (Supports longevity, Delivers wide-ranging antioxidant protection and supports enzyme systems) --> not in my regimen, I don't remember exactly but I found some unwanted effects.
• Acai Berry Extract (high potency antioxidant formula that helps increase vitality and combat free radicals) --> fine. I just drink blueberry juice instead. Dried Goji is also cheap. You get more for less that way.
• NAC-L/Cysteine (free radical fighter, very powerful anti-oxidant. Boosts liver healthiness) --> I take NAC to fight inflammation. Will take NAC in the future when flying (radiation and dry air). I don't take it on a regular basis, I don't want to down regulate my natural defences.
• Pomegranate Extract (Promotes proper liver and cardiovascular system maintenance, strengthening immune system, strong anti-oxidant) --> nothing wrong with that, but why not just drink the juice or other products instead of extract?
• Spirulina (Delivers powerful antioxidant support, potent joint health and more) --> looks fine to me, but not in my stack. I recall vegans take it a lot?
• Weed Grass (Energizing, whole-food nutrition) --> no idea
• Broccoli Extract Sulforaphane (Fights free radicals with broccoli's active ingredient) --> once again, why not just eat broccoli once in a while?
• Cinamon (Promotes blood sugar health already within a normal range) --> no idea, I have a diet with a lot of fibre so sugar should be in check.
• Chlorella (Features a comprehensive blend of vitamins, minerals, amino acids and antioxidants) --> similar to spirulina?
• Methylcobalamin B-12 (makes a difference in the health of the peripheral nerves, boost of energy, boost for mental functions ) --> in general, B12 bioavailability is poor, so take it 2-3 times daily. High doses won't help. It's in my multivit.
• Coconut Oil (From what I have heard a wonderful ingredient to cook with, to apply on your and on your hair) --> not the best oil for cooking, I use canola. Coconut has a strong smell. For hair I'd go with special products. Flax seed oil is good for cooking, too. I am not fully sure about olive oil, origin and quality may play a bigger role since the omega-3 content isn't that high. I never heard about C60oo before I joined this forum but I cannot imagine it's really a good idea to mess around with lipophilic nanoparticles.
• Ashwagandha (to reduce stress, reduce anxiety, build muscle and promote relaxation) --> no experience, seen it in the stores. For the purpose I would try it. Everyone is individually different to these herbs. Try one herb after the other.
• Rhodiola (against anxiety and to reduce stress) --> see Ashwagandha
• Schizandra (against anxiety and to reduce stress) --> see Ashwagandha
• Lysine-one (against anxiety and to reduce stress) --> no idea. I don't think there's a big need to supplement normal aminoacids or close derivatives with a healthy diet.
• Bacopa (For memory enhancement) --> looks fine, I would go for it. I haven't considered it yet but it's getting on my shortlist.
• White tea (good for general health and mental boost) --> nothing I use. It's like white vs. red wine, less potent. I stick with green tea / red whine.
• Green Tea Extract (good for general health and mental boost) --> absolutely. Use it a lot. There are even green tea mints (Sencha) out, so you add fresh breath. Excellent stuff.
• Acetyl-L-Carnitine (Provides antioxidant protection throughout the nervous system, passes through the blood-brain barrier to support cognitive health & optimal brain function, improves concentration and support memory) --> something I will have to research in more detail, but looks good on first review.
• Vitamine D3 (The sunshine vitamin. Supports bone, immune, emotional health and more and support happiness) --> absolutely, in summer months not essential, it's part of most multivits. I think 1000 I.U./day is enough.
• Curcumin (Promotes proper liver and cardiovascular system maintenance, strengthening immune system, strong anti-oxidant) --> I tried Turmeric and still use it, it's cheap and contains some low amounts of Curcumin. With Curcumin alone at high doese I have the same issues that I have with Resveratrol.
• Omega 3 (Ultra) (Support cardiovascular health and overall wellness) --> absolutely, 1000mg a day or two capsules. Refrain from some store brands with low omega-3 content, check the labels. There are some good deals, I think 30$ can get you through the year. I use a capsule together with lipophilic supplements to enhance their bioavailability.
• Ubiquinol (Boosts energy levels and overall health, inhibits inflammation) (more important when I become older though) --> IMO that's for old people with old mitochondria. I read it can have serious implications if you are ever short on oxygen (stroke etc.). There's an alternate but I haven't researched it as I don't need it at this stage.
• Multivitamin (What is the best brand? Ultimate Dialy Support?) (For general health) -->Mine is called Spectrum Gold. One tablet a day. It says for people over 50, that usually guarantees higher doses (I am younger than that). There are things like Chromium and Molybdenum that are hard to control any other way. Currently I cut mine in half and take them in the morning and evening, mainly due to poor vitamin B absorption. I accidentally bought another brand, it's not bad but I missed that the label was for 3 tablets. That stuff has also some added herbs like Astragallus, but it's like 6 mg when you should take 100times more to have any effect at all.
• Garlic Extract (Aids cardiovascular and immune system function) --> not sure, it doesn't harm but I think the benefits of extracts aren't that great. There has been good marketing in the past to make it popular.
• Alpha Lipoic Acid (Ultra-potent support for healthy glucose metabolism, possesses quality antioxidant properties that rejuvenate other antioxidants) --> once again, I need to revisit why I haven't added it to my stack yet. Blame it on information overload or I just need better nootropes.
• Magnesium (to reduce stress and insomnia, to reduce anxiety) --> it's good against cramps, especially women take it. Or if you do serious work outs, run marathon etc. I think there's a bit in my multivit.
• Country Life calcium magnesium complex (For my general magnesium and calcium level, may substitute the magnesium supplement. For general health) --> no issue, you don't need the extra magnesium.
• Zinc (for increased testosterone production (+ acne drug)) --> I use it for a while and it's my absolute favorite. Strong immune system, I rarely get a cold or fever and if, it's not severe. I don't have acne and I don't see any issue with my testosterone. I used 5mg per day but now I think it should be 10mg, the bioavailability isn't great, something I didn't know previously. 25mg or even 50mg I only take if I feel a cold/flu may be on the horizon.
• Selenium (Promotes heart and prostate health, is also a good way to shore up your body's antioxidant defenses) --> part of Multivit, I don't think I need extra.
• Silver (Helps the immune system defend the body) --> no-go. Especially colloidal silver is terrible, you can dye your skin that way.
• Boron (Against prostate cancer and good for the bones) --> may be part of multivit, not high on my priority list.
• Probiotics (for a general strong immune system boost) --> not high on my priority list, mainly a marketing thing. It doesn't harm but is often overprized.
• Maca (for increased libido) --> I would try it if libido is a concern to you.
• Tribulus Terrestris Extract (for increased performance (sports, especially heavy weight lifting) + increased libido) --> no idea
• Whey Protein (Enhances your workouts by providing terrific muscle nutrition, improves recuperation) --> no experience, but there's a whole industry.
• Inneov Solaire Intesif (For skin protection against the sun during the summer months) --> not sure what that is. I would go with an SPF-60 (I like sprays) and don't forget about a lip balm (I use a brand called Burt's, has pommegranate taste. I've seen someone having the lips redone by the MD (repeatedly shaving of layers of skin, that's one ugly business). I apply that Burt's lip balm also in winter with our dry air hear up North. If possible, just avoid too much sun exposure. Too bad tan looks great but is really not healthy.

[leclochard]

@ Andeay

No, I am not 40+, I am 24 actually. So I agree with you that I probably won't need all of these supplements, but I would still like to start living the optimal healthy life. Also I'm looking which supplements I can combine in a regimen for my parents (59 and 62), so basically I just want to know which supplements can be brought together in one regimen, without nullifying the effect of other supplements in the regimen. Everything else that has the same effect as things that are already in the regimen, is redundant for me. I excersise regularly and I already eat and drink healthy. I will take a look at milk thistle, vitamin K and K2. Could you give me sources and suppliers for the effects of C60 and metformin btw?

@ DorianGrey

Thanks for all the input! Very useful Canola oil I won't use, since I have found a lot of studies claiming it is not so healthy. I will cut silver out of the regimen, it is true that it is a bit controversial. I don't agree about the Resverarol though, I will take it in low amounts (50/day), which I think won't do any harm.

So high on my list are now:

- Zinc, Selenium, (Magnesium), Calcium (maybe all-in-1 capsule)
- Resveratrol+Pterostilbene, Xantahumol, NAC, ALCAR, Omega-3, Ubiquinol (I think starting with low dose isn't a bad idea), Vitamin D3, Vitamin K+K2, Methylcobalamin B-12, Alpha Lipoic Acid, Milk Thistle?, Multivitamin, (Anti disease+Longevity boost)
- Curcumin/Turmeric, Garlic extract, Cinamon, Weed grass, Sprilulina/Chlorella, Pomegranate/Acai/Dried Goji (Maybe as powder to make a shake of it)
- White Tea+Green Tea (they both have there health benefits imo) (drinks for during the day+my 3 black coffees)
- Coconut Oil (to cook)
- Ashwagandha, Rhodiola, St. Johns (added it after reading good reviews), Bacopa (relaxation, anti-anxiety+focus)
- Inneov Solaire Intesiv/Other Betacarotene + Good everyday sun protection cream (For skincare)
- Once I will hit the gym: Maca, Tribulis Terrestris Extract, Whey Protein (Simply for energy and recuperation of the muscles)

I hope people can tell me what they think about it

Edited by leclochard, 16 May 2013 - 10:29 AM.

[noot_in_the_sky]

Have you consider taking longjack and avena sativa, as well. Specially longjack, since it's much more cost effective then maca.

Bacopa have some negative site effects on the male libido, so perhaps it can affect your performance in the gym.
http://www.yourhormo...ysfunction.html

Functional mimetics are clinically valuable for targeted functions of testosterone, progesterone and estrogen without binding to hormone receptors. An example of an herb used as a functional mimetic of estrogen is Bacopa monniera [4], which mimics the abilities of estrogen to help the body adapt to both acute and chronic stress as well as maintain cognitive function, though it does not bind to estrogen receptors.

Selenium and NAC have a good interaction read this study:
https://www.ncbi.nlm...pubmed/19091331

J Urol. 2009 Feb;181(2):741-51. doi: 10.1016/j.juro.2008.10.015. Epub 2008 Dec 16.
Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study.
Safarinejad MR, Safarinejad S.
Source

Urology and Nephrology Research Center, Shahid Beheshti University, MC, Tehran, Islamic Republic of Iran. safarinejad@unrc.ir

Abstract

PURPOSE:

We explored the efficacy of selenium and/or or N-acetyl-cysteine for improving semen parameters in infertile men, and the associations among semen quality and the concentrations of selenium and N-acetyl-cysteine in seminal plasma.

MATERIALS AND METHODS:

The study included 468 infertile men with idiopathic oligo-asthenoteratospermia who were randomized to receive 200 microg selenium orally daily (selenium group of 116), 600 mg N-acetyl-cysteine orally daily (N-acetyl-cysteine group of 118), 200 microg selenium plus 600 mg N-acetyl-cysteine orally daily (selenium plus N-acetyl-cysteine group of 116) or similar regimen of placebo (control group of 118) for 26 weeks, followed by a 30-week treatment-free period. These patients provided blood samples for the measurement of serum testosterone, estradiol, follicle-stimulating hormone, luteinizing hormone, prolactin, inhibin B, selenium and N-acetyl-cysteine. Semen samples were also obtained for routine semen analysis, and the measurement of seminal plasma selenium and N-acetyl-cysteine.

RESULTS:

In response to selenium and N-acetyl-cysteine treatment serum follicle-stimulating hormone decreased but serum testosterone and inhibin B increased. All semen parameters significantly improved with selenium and N-acetyl-cysteine treatment. Administering selenium plus N-acetyl-cysteine resulted in additive beneficial effects. A significant positive correlation existed between the seminal plasma concentrations of selenium and N-acetyl-cysteine, and semen parameters. A strong correlation was observed between the sum of the selenium and N-acetyl-cysteine concentrations, and mean sperm concentration (r = 0.67, p = 0.01), sperm motility (r = 0.64, p = 0.01) and percent normal morphology (r = 0.66, p = 0.01).

CONCLUSIONS:

These results indicate that supplemental selenium and N-acetyl-cysteine improve semen quality. We advocate their use for male infertility treatment.

Edited by noot_in_the_sky, 16 May 2013 - 01:06 PM.

[noot_in_the_sky]

Also a good replacemen for bacopa are ginkgo biloba and lemon balm( melissa officinalis):

https://www.ncbi.nlm...pubmed/12888775

Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties.
Kennedy DO, Wake G, Savelev S, Tildesley NT, Perry EK, Wesnes KA, Scholey AB.
Source

Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle upon Tyne, UK. david.kennedy@unn.ac.uk
Abstract

Melissa officinalis (Lemon balm) is a herbal medicine that has traditionally been attributed with memory-enhancing properties, but which is currently more widely used as a mild sedative and sleep aid. In a previous study it was demonstrated that a commercial Melissa extract led to dose-specific increases in calmness, and dose-dependent decrements in timed memory task performance. However, the extract utilized in that study did not exhibit in vitro cholinergic receptor-binding properties. The current study involved an initial screening of samples of M. officinalis for human acetylcholinesterase inhibition and cholinergic receptor-binding properties. The cognitive and mood effects of single doses of the most cholinergically active dried leaf were then assessed in a randomized, placebo-controlled, double-blind, balanced crossover study. Following the in vitro analysis, 20 healthy, young participants received single doses of 600, 1000, and 1600 mg of encapsulated dried leaf, or a matching placebo, at 7-day intervals. Cognitive performance and mood were assessed predose and at 1, 3, and 6 h postdose using the Cognitive Drug Research computerized assessment battery and Bond-Lader visual analog scales, respectively. In vitro analysis of the chosen extract established IC(50) concentrations of 0.18 and 3.47 mg ml(-1), respectively, for the displacement of [(3)H]-(N)-nicotine and [(3)H]-(N)-scopolamine from nicotinic and muscarinic receptors in the human cerebral cortex tissue. However, no cholinesterase inhibitory properties were detected. The most notable cognitive and mood effects were improved memory performance and increased 'calmness' at all postdose time points for the highest (1600 mg) dose. However, while the profile of results was overwhelmingly favorable for the highest dose, decrements in the speed of timed memory task performance and on a rapid visual information-processing task increased with decreasing dose. These results suggest that doses of Melissa officinalis at or above the maximum employed here can improve cognitive performance and mood and may therefore be a valuable adjunct in the treatment of Alzheimer's disease. The results also suggest that different preparations derived from the same plant species may exhibit different properties depending on the process used for the sample preparation.

https://www.ncbi.nlm...ubmed/23653088

Plant-Based Medicines for Anxiety Disorders, Part 2: A Review of Clinical Studies with Supporting Preclinical Evidence.
Sarris J, McIntyre E, Camfield DA.
Source

Department of Psychiatry and The Melbourne Clinic, Faculty of Medicine, University of Melbourne, 2 Salisbury Street, Richmond, VIC, 3121, Australia, jsarris@unimelb.edu.au.

Abstract

Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of general anxiety and specific anxiety disorders. However, a comprehensive review of plant-based anxiolytics has been absent to date. Thus, our aim was to provide a comprehensive narrative review of plant-based medicines that have clinical and/or preclinical evidence of anxiolytic activity. We present the article in two parts. In part one, we reviewed herbal medicines for which only preclinical investigations for anxiolytic activity have been performed. In this current article (part two), we review herbal medicines for which there have been both preclinical and clinical investigations of anxiolytic activity. A search of MEDLINE (PubMed), CINAHL, Scopus and the Cochrane Library databases was conducted (up to 28 October 2012) for English language papers using the search terms 'anxiety' OR 'anxiety disorder' OR 'generalized anxiety disorder' OR 'social phobia' OR 'post-traumatic stress disorder' OR 'panic disorder' OR 'agoraphobia' OR 'obsessive compulsive disorder' in combination with the search terms 'Herb*' OR 'Medicinal Plants' OR 'Botanical Medicine' OR 'Chinese herb*', in addition to individual herbal medicines. This search of the literature revealed 1,525 papers, of which 53 plants were included in the review (having at least one study using the whole plant extract). Of these plants, 21 had human clinical trial evidence (reviewed here in part two), with the other 32 having solely preclinical evidence (reviewed in part one). Support for efficacy was found for chronic use (i.e. greater than one day) of the following herbs in treating a range of anxiety disorders in human clinical trials: Piper methysticum, Matricaria recutita, Ginkgo biloba, Scutellaria lateriflora, Silybum marianum, Passiflora incarnata, Withania somniferum, Galphimia glauca, Centella asiatica, Rhodiola rosea, Echinacea spp., Melissa officinalis and Echium amoenum. For several of the plants studied, conclusions need to be tempered due to methodological issues such as small sample sizes, brief intervention durations and non-replication. Current evidence does not support Hypericum perforatum or Valeriana spp. for any anxiety disorder. Acute anxiolytic activity was found for Centella asiatica, Salvia spp., Melissa officinalis, Passiflora incarnata and Citrus aurantium. Bacopa monnieri has shown anxiolytic effects in people with cognitive decline. The therapeutic application of psychotropic plant-based treatments for anxiety disorders is also discussed, specifically Psychotria viridis and Banisteriopsis caarti (ayahuasca), Psilocybe spp. and cannabidiol-enriched (low tetrahydrocannabinol (Δ9-THC)) Cannabis spp.

Edited by noot_in_the_sky, 16 May 2013 - 01:25 PM.

[DorianGrey]

I looked a lot into the oils used for cooking. Canola and Flax seed seem to be the oils with an excellent omega-3 to omega-6 ratio. High omega-6 promotes inflammation, so maize oil and even sunflower is pretty bad. Olive oil is somehow on the edge in this regard, but from what I've read it has high amount of a simple antioxidant. It also has certain omega-9 fatty acid that suppress the hunger feeling, so you tend to eat less. Canola is very cheap in good qualities and use is even recommended for a healthy heart.

I think Resveratrol at low doses isn't an issue, there is at least one population that lives long and drinks wine with some of the highest known Resveratrol contents. I am just not sure about the supplements.

I take about 150mg Turmeric (I see the Curcumin in a similar way like the Resveratrol based on the literature). It is cheap, I fill my own capsules. I am not sure if it is good to use as a spice or powder, I had the impression it stains teeth yellow. For sure you can stain your skin with the powder for a couple of days. It's got a low priority in my own regimen, it's in because of a positive cost/benefit ratio.

Vitamine K2 is in long-leaf salad (Kale is best). I don't think it's necessary to supplement. If you want to help your parents I would highly recommend 4-6mg/day Astaxanthin (take with fat/oil). Macular is an age related disease and severely impacts eye-sight in a large proportion of the elderly population. I started taking it a few weeks ago and my eye-sight already seems to improve, although I started it just for long-term prevention of A2E build-up. My Multivit also has 0.5mg of Lutein, not much but it helps.

After reading more on Milk Thistle I will add this to my regular stack. A lower dose for permanent use (liver health) and when I'll start my 4 months Telomerase boost I will go with a formulation that has best bioavailability. At your age it's probably not necessary except you do social drinking.

[leclochard]

Okay, thanks all for the replies!

If you go for olive oil though, take the extra virgin ones of good quality and use them especially for salads and stuff. As soon as you start frying, it already becomes worse. I tend to make nowadays everyday a toast in the afternoon like 'merienda' around 6: cereal bread lightly toasted, with a layer extra virgin olive oil, on top of that the juice of a squeezed tomato, a bit of salt and a bit of oregano. Lovely, tasty and rather healthy I reckon

Edited by leclochard, 28 May 2013 - 10:40 AM.