Good morning friends,
I have quite a bit of experience with a drug called Adderall. It is a mixture of
dl-amphetamine aspartate monohydrate
dl-amphetamine sulfate
dextroamphetamine saccharate
and dextroamphetamine sulfate.
Years ago, when I would abuse the drug, I would take doses from 80mg to 120mg in a day. Using it therapeutically, I would take 30mg per day.
While the drug is active in my system I feel exactly how I want to feel (during abuse and therapeutic use). This is why I'm using the drug as a point of reference to judge other pharms, nootropics, and research chemicals. I intend to find a safer,less addictive drug to use with less side effects.
I understand that a healthy lifestyle plays a major role in feeling healthy. My diet is almost vegetarian, with the exception of chicken primarily. I've significantly reduced cigarette consumption with my electronic cigarette (from 15 to 4 cigarettes daily). I've recently stopped my cardio exercise regimen because I'd been running 10 to 15 miles a week for three years and I felt that I was officially doing more damage than good. I should hit the gym again soon, though. I also meditated for years, but I feel it wasn't helping depressive and anxious symptoms, but did help in other areas.
I will describe the effects I like and the effects I don't like.
When amphetamines first start to take effect my body starts to feel a bit lighter. I literally feel like I'm less subject to gravity than usual. It's like a pleasurable buoyancy.
-Is this analgesia?
-Is this noradrenaline?
-Is this opioid related?
http://www.ncbi.nlm....pubmed/23130899
http://www.ncbi.nlm....pubmed/15501295
http://www.ncbi.nlm....pubmed/24965531 (probably not opioid mediated?)
I start to generally feel some emotional excitement and increased locomotion, which I like. Shortly afterwards, my hands and feet get cold and clamy. This is likely vasoconstriction, which I don't like because it eventually makes my penis shrivel up a bit (I'd like to avoid this).
Then I get this wonderful bodily rush. Imagine being entirelly stressed with work and then, suddenly, somebody trustworthy starts to rub, grope, massage, and touch you in places that are aching for attention. It's actually feels very erotic and enjoyable to me.
Could this have anything to do with smooth muscle relaxation from adrenoreceptors? Increase in cAMP?
To be specific, I get this pleasant warmth within my lower abdomen while the bouyancy increases and my legs don't feel subject to gravity.
I'd love to find this mechanism of bodily pleasure. It happens to me with marijuana (sometimes), amphetamines, alcohol rebound, and hallucinogenic drugs. So my guess is that this has something to do with increased thalamic and cortical glutamate release/activity.
From this point forward I feel content, focused, professional, goal oriented, and motivated. All of which are likely attributable to dump of dopamine from nerve terminals into the nuccleus accumbens and the prefrontal cotex. Especially the tingles on the top of my head.
Positive effects aside. At this point I usually experience rapid dehydration and I have a few anxiety provoking heart palpitations (even on occasions with a single isolated does). I usually drink a half litre of water.
What role does vasopressin play in mediating the therapeutic effects of amphetamines? Those of you who've tried vasopressin nasal inhaler, what effects did you notice?
About 2.5 hours in, pleasurable tactile sensations are amplified. If I gently stimulate my testicles, my entire body and mind is overcome with pleasure and relaxation within five seconds. Again, I'm thinking this is due to increased glutamatergic activity in the thalamus and the cortex and dopamine in the NAcc.
The focus enhancement, emotional excitement, and sexual arousal continue for another 2 hours and gently fade away. The next day I feel generally fine with some light cognitive issues that fade after about 48 hours.
In normal sobriety, I have a lot of dark thoughts that tend to bring me down emotionally and motivationally. My mind will venture into possible random potential situations of extreme loss and devastation. All I need is a pleasurable distraction/diversion. I feel a sustainable increase in hedonic tone is appropriate, which is probably true for everybody, all the time.
I also take:
"from the earth" multivitamin
1300mg of EPA fish oil
800mg Aniracetam
lots of coffee
nicotine
marijuana
MY QUESTION → Are there any drugs, nootropics, research chemicals that:
-exert a clinically significant increase in activity at dopamine receptors in the nucleus accumbens and prefrontal cortex?
-increase glutamatergic activity in the thalamus and the cortex
-provides an analgesic effect
-"bouyancy"
-provide locomotor stimulation, "focus", goal oriented activity, etc.
I was thinking perhaps:
Ethylphenidate
2-FMA
9-methyl-betacarboline
selegiline
BPAP
7,8 dihydroxyflavone
Bromantane
Neuropeptide S (safety?)
Cabergoline (although I'd prefer Lisuride due to 5-HT2B activity)
Alpha-PHP (probably not, but availability makes this one easier, but definitely not safer than adderall)
3,4-CTMP (If I can find US domestic source)
Anybody have experience with these? Can you recommend them?
Are ther any ampakines, racetams, or more obscure drugs (idra-21 and prl-8-53) that increase tactile sensitivity and sexual arousal?
I ask that you share your experiences. I'm really close to trying selegiline or 9-methyl-betacarboline. To what extent does selegiline enhance sexual arousal?
I am 24, 150lbs, and 5'11"
You are all incredible people!! Thank you!!
Also, are there any other forums I can get good information and anecdotal reports?
Edited by Shulginstestsubject, 16 December 2014 - 09:25 AM.