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Having doubts about Alpha Lipoic Acid as an anti-ageing supplement. What are your thoughts?

alpha lipoic acid ala

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#1 cjacek

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Posted 30 January 2024 - 02:15 PM

Hi,

If I understand correctly, the protective effects of Alpha Lipoic Acid are mediated by hormetic mechanisms, which means inducing low levels of ROS that activate a number of cell protective antioxidants. This is all great but in an older person, for example, where there is a lot of ROS already, the cell basically falling apart, is it a good idea to increase ROS? Wouldn't you want to do the opposite? I mean specifically in an old person. Wouldn't that actually increase ageing potentially and increase disease risk? That's why I'm having doubts about ALA or maybe I'm looking at it the wrong way?



#2 Mind

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Posted 30 January 2024 - 06:08 PM

From what I have read in the past, ALA was (and still is) in the category of anti-oxidant, so it would seem that it would be beneficial in reducing the ROS that increases with aging.


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#3 Neurocryo

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Posted 05 February 2024 - 02:11 AM

I’ve taken it in the AM for about a year and a half 2 years.  I feel as though it lowers my blood sugar.  Sometimes this isn’t good as I find myself looking for a snack a half hour after taking it.  If you can stand it I think most would agree that lowering your blood sugar is better if it is normally slightly elevated like mine.  I took it before coffee because I think even black coffee causes a blood sugar spike.


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