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Noopept less effective in those who do CR?

Started by InquilineKea , Apr 22 2014 04:39 PM
noopept

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#1 InquilineKea

InquilineKea
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Posted 22 April 2014 - 04:39 PM

Just wondering. CR tends to suppress protein synthesis (due to mTOR inhibition), as does methionine restriction.

 

But Noopept increases BDNF/NGF, which help increase protein synthesis.

Does CR inhibit Noopept's beneficial effects?


#2 Jim Morrison

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Posted 22 April 2014 - 08:50 PM

I would say on the opposite. Reduced nutrient (aminoacid) induced background activity of mTORC1 should sensitize the dentritic compartment to local activation by bdnf.


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