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Fight Aging News
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A Rare Reduced Function Mutation in cGAS in a Long-Lived Human Lineage
That genetic variation appears to determine littl...
Yesterday, 07:22 PM Read Full Story -
Longevity Investors Lunch 2026
Longevity Investors announces the upcoming Longev...
Yesterday, 04:22 PM Read Full Story -
Succinic Acid Supplementation to Provoke Greater Histone Succinylation
Histones are structures in the cell nucleus that...
Yesterday, 11:22 AM Read Full Story -
A Framework for Messenger RNA Cancer Vaccine Development
Researchers here discuss the application of lipid...
Yesterday, 11:11 AM Read Full Story -
Energy Metabolism Appears Important in Mouse Models of Alzheimer's Disease
The proof of concept demonstration outlined in to...
Jan 01 2026 07:19 PM Read Full Story -
Senotherapeutics to Treat Brain Aging
Companies working on novel therapeutics targeting...
Jan 01 2026 11:22 AM Read Full Story
Articles
'Nugenics' - breakthrough rejuvenation?
Discussion of a recent preprint by Horvath/Katcher et al. reporting rejuvenation in mice with an undisclosed blood component.
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Eternus by Neurohacker Collective
A 36 Ingredient Formula for Comprehensive Cell Energy & Aging Support
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Pioneers: Marquis de Condorcet (1743-1794)
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Cryonics
The following is a quick overview on Cryonics. NB: The information below is periodically reviewed for accuracy, but LongeCity makes no representations or gives any warranties whatsoever that the following information is accurate and complete at an...
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Aging Theories: is an 'aging program' a...
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Antioxidants- relevant for life extension?
by Vit Zemanek
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Nootropics in human trials (Intro)
by Lukas
Due to further advances in the field of neuropharmacology new possibilities of cognitive self-enhancement emerge.
Some are marketed as ‘smart drugs’, cognitive enhancers or nootropics.
This article aims to provide a brief overview.
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Aging theories: Is there a unifying factor in a...
by: Vit Zemanek
- evolutionary approach to the process of senescence
- programmed theories of aging
- error theories of aging
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Geroprotector Review: Rapamycin and other mTOR...
Sven Bulterijs continues his discussion of prominent compounds with potential life extension efficacy by looking not just at rapamycin but also at its target, the mTOR pathway, which has likely a key role in mediating lifespan. ⇒ read the article i...
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Metformin - a geroprotector?
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information...
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Aschwin de Wolf: Cryonics
(interview Feb. 2017)
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Why do some turtles outlive humans?
by Vit Zemanek
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Article: Gut microbiome in health and aging
As part of his new column "Sven's Science Corner" Sven Bulterijs discusses novel insights into the crucial role gut bacteria seem to play in health, disease and aging. ⇒ read the article in "Sven's Science Corner" blog
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