LongeCityAdvocacy & Research for Unlimited Lifespans
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Fight Aging News
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Endothelial Cellular Senescence Contributes to Loss of Capillary Density
The consensus of the research community on senesc...
Yesterday, 06:44 PM Read Full Story -
Autophagy Is Essential for Healthy Muscles
A study published in Aging Cell has reported that...
Yesterday, 04:14 PM Read Full Story -
Gut Microbiome Composition Correlates with Longevity in Rabbits
The balance of microbial populations making up th...
Yesterday, 10:22 AM Read Full Story -
An Interview with Reason of Repair Biotechnologies on Reversal of Atherosclerosis
As some of you may know, I co-founded Repair Biot...
Yesterday, 10:11 AM Read Full Story -
Sea Urchins as a Model of Negligible Senescence
Species that exhibit negligible senescence tend t...
Apr 17 2024 07:03 PM Read Full Story -
Quercetin Delays Ovarian Aging in Middle-Aged Mice
A recent paper published in Nature Aging dives in...
Apr 17 2024 04:19 PM Read Full Story
Articles Archives
8 Reasons to reach out to 'the public'
Mar 08 2015 11:34 PM |
ImmInst
in Articles
While the idea that drastic life extension may be an option for humankind in the future has been encountered by many through the media and fiction, the vast majority of the public do not grasp whether and how this could realistically apply to them or t...
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Pioneers: Marquis de Condorcet (1743-1794)
Dec 26 2018 10:36 AM |
G. Stolyarov II
in Articles
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Eternus by Neurohacker Collective
Dec 18 2019 12:46 PM |
ImmInst
in Articles
A 36 Ingredient Formula for Comprehensive Cell Energy & Aging Support
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Why do some turtles outlive humans?
Feb 09 2017 12:39 AM |
yoik
in Articles
by Vit Zemanek
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'Nugenics' - breakthrough rejuvenation?
Jun 28 2020 09:45 PM |
Ildathach
in Articles
Discussion of a recent preprint by Horvath/Katcher et al. reporting rejuvenation in mice with an undisclosed blood component.
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Cryonics
Apr 25 2018 10:52 PM |
benbest
in Articles
The following is a quick overview on Cryonics. NB: The information below is periodically reviewed for accuracy, but LongeCity makes no representations or gives any warranties whatsoever that the following information is accurate and complete at an...
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Aging Theories: is an 'aging program' a...
Apr 18 2018 05:45 PM |
ImmInst
in Articles
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Antioxidants- relevant for life extension?
Feb 18 2018 11:29 PM |
yoik
in Articles
by Vit Zemanek
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Metformin - a geroprotector?
May 19 2017 07:09 PM |
s123
in Articles
Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the recent findings and further background information...
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Geroprotector Review: Rapamycin and other mTOR...
Jul 18 2017 08:59 PM |
s123
in Articles
Sven Bulterijs continues his discussion of prominent compounds with potential life extension efficacy by looking not just at rapamycin but also at its target, the mTOR pathway, which has likely a key role in mediating lifespan. ⇒ read the article i...
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Nootropics in human trials (Intro)
Sep 09 2017 12:15 PM |
lukas_93
in Articles
by Lukas
Due to further advances in the field of neuropharmacology new possibilities of cognitive self-enhancement emerge.
Some are marketed as ‘smart drugs’, cognitive enhancers or nootropics.
This article aims to provide a brief overview.
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Aging theories: Is there a unifying factor in a...
Aug 20 2017 05:40 PM |
ImmInst
in Articles
by: Vit Zemanek
- evolutionary approach to the process of senescence
- programmed theories of aging
- error theories of aging
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Assessing the effects of c60 on human cancer pr...
Sep 06 2014 11:44 PM |
ImmInst
in Articles
View attachment: c60re02.png "Assessing the effects of c60 on human cancer proliferation in vivo"is led by life-extension trailblazer Kelsey Moody. It is interesting that he turns the attention of his new venture Ichor Therapeutics to...
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Supplement Review: Nicotinamide Riboside
Nov 18 2016 09:58 AM |
s123
in Articles
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Aschwin de Wolf: Cryonics
Feb 19 2017 12:50 PM |
s123
in Articles
(interview Feb. 2017)
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Article: Gut microbiome in health and aging
Jan 10 2017 05:59 PM |
s123
in Articles
As part of his new column "Sven's Science Corner" Sven Bulterijs discusses novel insights into the crucial role gut bacteria seem to play in health, disease and aging. ⇒ read the article in "Sven's Science Corner" blog
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Honorary Member: Fred Chamberlain (boundlesslife)
Apr 04 2013 09:28 PM |
caliban
in Articles
View attachment: fred.jpgIn the early 1970's Fred Chamberlain, together with his wife Linda founded the cryonics corporations Manrise and the Alcor Society for Solid State Hypothermia, The latter continues until today as the Alcor Life Extension Foun...
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LongeCity Science Initiatives - Autumn 2011 review
Oct 08 2011 12:34 PM |
caliban
in Articles
“To conquer the blight of involuntary death” is a complex task: political, economic, logistic, and social factors all play a role in making this dream a reality. Ultimately though, the challenge remains a scientific and technological one. We need to kn...
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"Healthy Aging" is not enough
Feb 09 2013 11:33 AM |
brokenportal
in Articles
A Response to the "Compression of Morbidity" Mindset "...there is no basis for the ardent hopes and positive statements made as to [its] safety and success[..], and [..] therefore, it would be a wrong, whet...
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crowdsourced multivitamin
Dec 17 2012 01:06 AM |
caliban
in Articles
Extending maximum human lifespan will likely require a wide range of new biotechnology. Powerful interventions such as pharmaceuticals, stem cell technology, and gene therapy are in development but could be years or decades away from widespread impleme...
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Carbon nanospheres almost double rat lifespan:...
Jul 14 2012 10:19 PM |
ImmInst
in Articles
by AgeVivo and Sven Bulterijs more discussion of the paper in question in this thread in the C60 Health sub-forum this article is a work in progress, it may change over time based on discussions and new information / Introduction In June of 2012...
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Metformin a life extension drug?
Dec 08 2011 11:28 PM |
s123
in Articles
by Sven Bulterijs For hundreds of years it has been known that a plant extract from the French lilac (Galega officinalis) improved the intense urination seen in diabetes patients. From this plant guanidine was extracted but it was too toxic for human u...
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Folding@Home Team
Nov 06 2011 07:33 PM |
brokenportal
in Articles
Use your computer's spare processing power to help cure disease!TheLongevity Meme has teamed up with Longecity to contribute to the Stanford Folding@Home distributing computing project – aimed at curing disease through understanding the basics of prot...
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Calorie Restriction Primer
Nov 18 2011 08:52 PM |
caliban
in Articles
by Sven Bulterijs & Paul McGlothin, Often described as the only proven intervention that extends mean and maximal life-span in mammalian species, it is also a lifestyle choice for the committed immortalist. But why and how does it work? How to begin...
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Crosslinks
Oct 07 2011 12:48 PM |
ImmInst
in Articles
by Johan Sjöberg The diseases and complications of aging are infamous –cardiovascular disease, cataracts, Alzheimer's disease, amyloidosis, cancer, and so on. Their effects are often debilitating, and one of them will always end up causing your death...
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