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Secret to a Longer Life? Don’t Ask These Dead Researchers

fasting longevity atkins brenner death

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#1 Oakman

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Posted 10 March 2018 - 12:05 AM


Food for thought... <--full length article.

 

"In the field of anti-aging and longevity research, self-experiments are all the rage. Valter Longo, director of the University of Southern California Longevity Institute, undertakes multiday fasts. Other scientists are dosing themselves with the diabetes drug metformin, believing it may help protect their cells from wear and tear. Charles Brenner, a biochemist, has drunk milk laced with high doses of nicotinamide riboside, a type of vitamin B that might defend against aging."

 

"Let’s start in the 1930s, when an American nutritionist named Clive McCay designed a low-calorie diet for his lab rats at Cornell that gave them all the nutrients they needed but kept them as thin as supermodels and (presumably) ravenous. ... But he didn’t make it close to 130. Though trim and athletic, he had two strokes and died at 69."

 

"Nathan Pritikin, one of the foremost champions of low-fat diets, died at 69, nearly the same age as Dr. Robert Atkins, who believed in the opposite regimen."

 

"It’s the decisions that we make as a collective that matter more than any choice we make on our own. ... When I asked Dr. Brenner about this, he agreed that the decisions that we make collectively might be the most important ones. He emphasized that the point of scientific self-experimentation should not be to live longer but to learn."

 

"When it comes to staying alive, we’re all in it together."


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#2 Oakman

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Posted 10 March 2018 - 12:19 AM

Noticed a commenter duly noted this, "Including Dr. Atkins untimely early death in a discussion centred around nutrition is unwarranted and misleading. Dr Atkins died of a head injury due to slipping on an icy sidewalk in front of his New York condo building. Nothing to do with nutrition manipulation"


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#3 Iporuru

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Posted 10 March 2018 - 10:13 AM

Noticed a commenter duly noted this, "Including Dr. Atkins untimely early death in a discussion centred around nutrition is unwarranted and misleading. Dr Atkins died of a head injury due to slipping on an icy sidewalk in front of his New York condo building. Nothing to do with nutrition manipulation"

 

It's a similar story with Nathan Pritikin who committed suicide due to severe pain and complications related to leukemia therapy:

"In the 1950s, Pritikin went through a series of high-dose radiation treatments for a skin condition, pruritus ani, that was stubbornly resisting all the pills and ointments he tried. Over the course of two months, he got blasted with a total of 220 rads (“radiation absorbed doses”) of unfiltered x-rays—the equivalent of getting 3700 chest x-rays or 22 million dental x-rays. Not surprisingly, it wreaked havoc: he soon ended up with a blood condition he’d battle for the rest of his life, later diagnosed as a rare form of leukemia. That all happened before he embarked on a low-fat diet.

Pritikin actually managed to keep his disease in remission for almost three decades, but in late 1984, saw an unfortunate resurgence of symptoms—including leg swelling so severe that he had to stop going on his beloved daily runs. His docs ushered him onto some experimental chemotherapy, telling him it was the only way he could ever resume jogging. Not only did the chemo not help, it also left Pritikin with crippling anemia, kidney failure, diabetes, all-consuming pain, and 30 pounds stripped off his already slender body. In February of 1985, he flew out to New York for a second opinion, was told his case was hopeless and he would certainly die within the next six months, and proceeded to take his own life in a hospital bed in Albany." from Denise Minger: https://deniseminger...art-1/#pritikin

and

http://people.com/ar...e-vol-23-no-10/
 


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#4 Matt

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Posted 10 March 2018 - 08:42 PM

Are you telling me I've wasted almost 15 years of my life doing CR?  ;)

 

Roy Walford never started CR until late in life and many of his symptoms appeared after biosphere 2 - which may have been part of the cause.

 

And to my knowledge, no one else who has been doing CR for a while has developed ALS. 

 

Not sure about McCay. Any reliable sources regarding his diet? 

 

"Clive exercised vigorously and was an avid skier. He controlled his diet, and was always lean and trim."

 

So why was he lean, was it exercise or CR? 

 


Edited by Matt, 10 March 2018 - 08:47 PM.


#5 Matt

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Posted 10 March 2018 - 08:59 PM

"Six of the original 20 monkeys have lived beyond 40 years of age, the previous maximal lifespan recorded, and one old-onset CR male monkey is currently 43 years old, which is a longevity record for this species."

 

" Importantly, the median survival estimates for old-onset males were very high, similar to what has been reported previously as the 90th percentile for this species (35 years of age). Six of the original 20 monkeys have lived beyond 40 years of age, the previous maximal lifespan recorded, and one old-onset CR male monkey is currently 43 years old, which is a longevity record for this species. 

https://www.nature.c...les/ncomms14063

 

 I also did a breakdown of these studies (which weren't perfectly designed in many ways). I intend to do a part two when we have more data.

 

But they want to pick out individuals. How about those rhesus monkeys that lived way longer than any on record.

 

Prior to the study: "Researchers analyzed data on the lifespan of 3264 rhesus monkeys, and only two 40-year old monkeys have ever [previously] been documented."


Edited by Matt, 10 March 2018 - 09:01 PM.

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#6 Oakman

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Posted 10 March 2018 - 10:20 PM

I think the point is that societal health improvements generally overide point improvements that one particular "longeveity" pill or regime can accomplish. Many of the researchers are looking for "the answer" to longevity. I doubt there is one single "thing" that will prove to be the fountain of youth for mankind. However, each discovery may be a step in the right direction, and when added to others, will result in avove average longevity for those who partake in all of them together..


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#7 BieraK

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Posted 11 March 2018 - 05:51 AM

I think that Valter Longo is one of the most systematic, cautious and careful researchers in the area of longevity. His Fasting Mimicking Diet is the best alternative to obtain all the benefits of fasting, in a way that is not painful, safe and compatible with daily life.


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#8 misterE

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Posted 20 March 2018 - 09:13 PM

That's what I don't understand about the popularity of low-carb diets. Look at what happened to Atkins. He died overweight with a history of heart-disease. And many other low-carb diet promoters look kinda oily and fat and have a soft estrogenic look to them. Atkins was not only fat bald and greasy, but had age spots and rotten teeth! In comparison you look at the people who promote low-fat plant-based diets and they look much more fit and attractive.


Edited by misterE, 20 March 2018 - 09:16 PM.

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#9 misterE

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Posted 20 March 2018 - 09:15 PM

 

 

It's a similar story with Nathan Pritikin

 

 

Also when Nathan Pritikin died, his circulatory-system was autopsied and was found to have had very clean arteries with very few atherosclerotic plaques. This finding was published in the scientific-literature too!


Edited by misterE, 20 March 2018 - 09:16 PM.

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#10 misterE

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Posted 21 March 2018 - 04:46 AM

https://www.ncbi.nlm.../pubmed/3889648


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#11 DbCooper

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Posted 29 March 2018 - 06:48 PM

That's what I don't understand about the popularity of low-carb diets. Look at what happened to Atkins. He died overweight with a history of heart-disease. And many other low-carb diet promoters look kinda oily and fat and have a soft estrogenic look to them. Atkins was not only fat bald and greasy, but had age spots and rotten teeth! In comparison you look at the people who promote low-fat plant-based diets and they look much more fit and attractive.

 

 

This is just a personal observation but, you have clearly never been a member of Vegan Grocery Co-OP before. The sole reason I moved away from  plant based only  diet was primarily based on the condition of the people I saw almost daily at this market.  Granted some of these people probably became vegetarian based on a medical diagnosis that befell them. Whole foods on the other hand which sells primary to omnivorous people seems to have a much more attractive clientele.  


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#12 RWhigham

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Posted 13 April 2018 - 05:56 PM

This is just a personal observation but, you have clearly never been a member of Vegan Grocery Co-OP before. The sole reason I moved away from  plant based only  diet was primarily based on the condition of the people I saw almost daily at this market.

 

During CR, the body reduces it's metabolic rate to survive famine. The body lowers metabolic rate by lowering thyroid T3. This adaptation can also occur with other diets such as time-restricted feeding, low carb, vegan, etc. 

 

Metabolic rate was once thought to be inversely related to lifespan.  This has been discredited between species, but perhaps accounts for the increased lifespan with CR within a species. 

 

Unfortunately, I suspect low T3 caused by diet can cause hypothyroid symptoms--of which, there is a long list. Most people may not recognize these symptoms. 


Edited by RWhigham, 13 April 2018 - 06:47 PM.

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#13 Matt

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Posted 15 April 2018 - 12:51 AM

In case any of you missed it, a recent study found that CR extended lifespan almost 50% in smaller primates.
 

See: http://www.crvitalit...small-primates/


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