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Extremely low Pregnenolone!

pregnenolone

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#1 John250

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Posted 12 June 2018 - 05:15 PM


I’ve gotten pretty much every hormone test you could think of but completely forgot about Pregnenolone. I’m on testosterone replacement therapy and my doctor usually tests all my hormones including progesterone but somehow negated pregnenolone. So I ordered the test and just got my results back and wow!

Pregnenolone LC/MS <5 range 22-237

Now I have to look up all the symptoms of low Pregnenolone. I’ve got a bottle of Douglas Labs Pregnenolone I’ll start ASAP. What’s the recommended dosage? Anyone ever have low levels and supplement with it? If so what were the benefits?

Thanks
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#2 Daniel Cooper

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Posted 12 June 2018 - 09:02 PM

I wonder if your low pregnenolone is an artifact of your TRT?

 

 

 

 



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#3 John250

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Posted 12 June 2018 - 09:16 PM

I wonder if your low pregnenolone is an artifact of your TRT?

TRT can definitely lower it up to 80%. I incorporate hcg at 250iu 3x/wk which is supposedly supposed to help regulate progesterone, dhea and pregnenolone. My dhea blood levels are in normal range in urine value is slightly above normal range. Progesterone was also a normal range when I got it checked a few years ago. I took 5mg pregnenolone from Douglas laboratories a few hours ago. Chewed up the pill and took it sublingual. I have an appointment in two weeks with my endocrinologist I’m sure I’ll need much more Pregnenolone since dosages average 50-200mg/day. I ordered some transdermal pregnenolone 15mg from life-flo which is the same company I use for transdermal DHEA 30 mg per day. I had a four-part saliva cortisol test done about a year ago and everything was pretty normal. I wonder if my low Pregnenolone is why exhibit so many symptoms of chronic fatigue syndrome. Hopefully this is my fix.

Also I just ordered a saliva sleep test kit from thorne To test court is all again as well as melatonin levels.

Edited by John250, 12 June 2018 - 09:21 PM.


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#4 John250

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Posted 13 June 2018 - 12:22 AM

Update:
I was looking through some old lab work and I noticed in May 2017 I had pregnenolone testedand it was normal
26 range 13-208 nd/dL

Back in 2015 my progesterone was about 4x the range but I was on steroids back then which increase it.

So this is all of that within only one year my pregnenolone went from 26 to <5. My TRT regimen has been the exact same so I’m puzzled.

Going to get a progesterone test done this week as well.





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