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David Sinclair recently upped his dose to 1,500mg

reveratrol sinclair dose

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#1 Chris Pollyanna

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Posted 10 November 2018 - 07:26 PM

On Peter Attia's excellent recent podcast with David Sinclair https://peterattiamd.../davidsinclair/ , Sinclair stated that he recently increased his resveratrol intake from 1 gram to 1.5 grams. He said that he had done this after receiving advice from another scientist "who shall remain nameless".


He also said that although he doesn't expect it to really increase his lifespan, he thought it would definitely be useful from a cardiovascular perspective.



#2 tunt01

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Posted 10 November 2018 - 08:47 PM

I just listened to the episode while running on the treadmill.  He recently upped his metformin to 1.5 grams / day.  He continues to take about 1 gram/day of resveratrol, which he acknowledges may or may not be doing anything but thinks its likely doing no harm (in the case of doing nothing).  His NMN dosage is 750 mg per day.


see the notes




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#3 Chris Pollyanna

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Posted 11 November 2018 - 09:51 PM

Oh my goodness, you're absolutely correct @tunt01, it's Metformin, not Resveratrol. Really sorry about that, I hate to provide incorrect information  :sad:


However, I do stand by my assertion that it is an excellent podcast & well worth a listen!

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#4 sthira

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Posted 12 November 2018 - 04:09 PM

To me, a telling thing from this his talking on this podcast is that he doesn't appear to know more about how to slow the aging process than anyone else. Despite his prestige and pedigree and money and devotion, he's aging right on schedule like anyone else.

I mean, Sinclair and his colleagues have spent their entire careers on this subject of age-reversal. He says he is upping his personal metformin experimental dosing (perhaps because some insider personal friend like Nir Barzilai told him it's ok).

He says he has "buckets" of resveratrol in his "basement" and that he knows the outcome of "doing nothing" with regard to aging: the body declines until it dies. He's been saying for nearly a decade that "We have coumponds that are a thousand times more effective than resveratrol" yet where are they? He's coming out with a book next year.
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