Hey everyone,
I've been searching for a safe benzodiazepine to use for my depression and anxiety. Imidazenil is a novel benzodiazepine partial agonist. The literature on it explains that it does not cause dependency issues or tolerance. Here's the Wiki on it:
Imidazenil[1] is an experimental anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil, and bretazenil.
Imidazenil is a highly potent benzodiazepine receptor partial agonist[2] with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic[3] effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold,[4] and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present.
Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety,[5] a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents,[6][7] and as a novel treatment for schizophrenia.[8]
There are no human studies on it, despite it being highly promoted as a novel benzodiazepine for anxious states without the development of tolerance, high, or rebound effects.
I have found a supplier on Alibaba willing to synthesize it at 1000 USD for 25g.
Imidazenil is highly potent and has a half-life of 10 hours.
If anyone is interested, I recommend reading the studies available on its properties to decide for yourself if all his is true.
I plan on getting 5 participants, myself included to trial this compound.
Best regards.