Same. CBD helped for awhile, then wore off. Took a few months off of it, then tried again, still nothing. I suppose my body adapted, so now it’s useless in the battle. I think CBD with low dose THC can be helpful (at least until homeostasis sets back in...)
I’ve tried nearly all the pharmaceuticals and supplements you’ve listed — a dozen or so anti-depression meds, nothing... along with a healthy whole food plant based diet, regular exercise, calorie restriction, fasting, proper sleep hygiene principles (whatever that means), having friends, then not having friends, being alone, being in groups, having a good job, then having a bad job, then no job, having money, then having no money, staying busy, then doing nothing, meditation, then no meditation, yoga, then no yoga, having dreams and goals and a purpose to keep living, then being adrift...
Nothing seems to work for me. I’ve mostly given up on curing depression.
Daily Exercise: helps a lot.
Of everything, I’d say consistent exercise was best. So I did that and did that and did that and did that.... until I became a professional exerciser, then injuries piled up around me like plastic pill bottles. I’d get some stupid injury (...I felt a pop in my calf, followed by sharp pain that lasted a few years; then it was the broken left toe, followed by left ankle, right knee then left knee, right hip, lower back, then my left shoulder... one injury after another) so so much for exercise as a cure for depression when you’re obsessive compulsive about it and must always be the very best and most talented in the space.
My conclusion is nature and evolution is “trying stuff” (though no really) all the time — randomly, of course, no point to anything at all — and some of beings were hardwired to be happy (I’ve met people in rough, terrible shanty towns who live way happier and are better adjusted than I’ve ever been) and some of nature's little experiments were born messed up, never happy or satisfied, obsessive or compulsive or both, and depressed and anxious, both, and some of us are just.... struggling always with maintaining dignity and grace.
Other than being born anew into an entirely different body, I don’t see much hope for cures. Certainly doesn't want to come from science, does it, we wait and we wait and we read about all the promising new interventions, then they disappear anyway, our hopes right along with them. Whatever... life is short anyway.
Edited by sthira, 29 September 2019 - 08:07 PM.