This topic is lockedThe clinical science for NAD+ precursors is still in its slow and steady phase.
Research has confirmed that taking NMN (Nicotinamide Mononucleotide) or NR (Nicotinamide Riboside) effectively raises NAD⁺ levels in the blood. However, there is a gap in the science.
We can boost NAD+ levels but don’t yet know if this actually slows the biological clock or extends human lifespan. Most longevity claims are extrapolated from mice and yeast, which don’t always translate to humans.
Many successful clinical trials use between 500 mg and 2000 mg per day to see a significant physiological change. Even with a high dose, NAD+ molecules are fragile. If the supplement isn't formulated well, much of it can be broken down by the digestive system before it ever reaches your cells.
So is it worth taking them, especially given how expensive they are?
