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The Dopamine ~ Iodine connection

dopamine iodine

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#1 Arjuna

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Posted 25 January 2014 - 03:16 AM


74% of adults are iodine deficient. Iodine is required to make T3 and T4, if the body doesn't have enough of these thyroid hormones then the hypothalamus secretes TRH (Thyrotropin-releasing hormone)which releases TSH (Thyroid-stimulating hormone) and prolactin (1). Prolactin, as we all know, is antagonistic to dopamine. The TSH that is released from the anterior pituitary gland further lowers dopamine (2). If the thyroid doesn't create T3 and T4 the TSH levels keep climbing, and dopamine will keep dropping.


(1) TRH increases prolactin and decreases dopamine http://www.ncbi.nlm..../pubmed/6796383
(2) Dopamine antagonist raises TSH http://www.ncbi.nlm....v/pubmed/436307


I'm currently on Iodine (5mg/day) and the Mr. Happy Uridine stack, and there is some nice synergy here; I feel balanced, happy, energetic, and my imagination is vivid and alive again.

Edited by Arjuna, 25 January 2014 - 03:17 AM.


#2 xks201

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Posted 25 January 2014 - 03:24 AM

Are you on iodide or iodine? What brand? What is in happy stack?

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#3 Arjuna

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Posted 25 January 2014 - 03:27 AM

Mr. Happy Uridine: http://www.longecity...ne-uridine-dha/

Potassium Iodide, from kelp. I will be trying lugol's iodine soon.

Edited by Arjuna, 25 January 2014 - 03:28 AM.


#4 Fred Downson

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Posted 25 January 2014 - 05:21 PM

h

Edited by Blair Durbin, 25 January 2014 - 05:34 PM.


#5 rwac

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Posted 25 January 2014 - 05:55 PM

Btw, excess iodine can raise TSH too.

http://www.ncbi.nlm....ubmed/11396709/

#6 8bitmore

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Posted 25 January 2014 - 10:18 PM

from: http://drsircus.com/...kinsons-disease

Long-term iodine deficiency appears to be linked to abnormalities in the dopaminergic system including an increased number of dopamine receptors. It is argued that this raises susceptibility to dopamine oxidation, which in turn causes deficiencies of the antioxidant enzymes Cu/Zn superoxide dismutase, glutathione peroxidase and catalase. Dopamine deficiency also leads to elevated cytotoxic glutamate levels.

The hypothesis that Parkinson’s disease may be linked to soil and hence dietary iodine deficiency, associated with glaciation, is not new. In 1987, De Pedro-Cuesta[9]concluded that Parkinsonism had the strongest links with “early life exposure to a geochemical imbalance, related to the last glaciation, associated to iodine washing out, present in soil, water and diet.”

The page also lists constipation as a side-effect of Parkinson's (or perhaps more correctly iodine/dopamine-disruption?) - anecdotally I can say that I've gone from being always on/off irregular bowel-movements (for all of my life) to completely 100% regular after I started one drop of 2% lugols daily. The effect is startlingly clear and nothing else I've tried before (pre/pro-biotics, diet, cutting sugar, exercise, and a myriad of supplements) have had anywhere near that efficiency.

#7 NeuroNootropic

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Posted 05 February 2015 - 09:50 PM

Which 74% of adults are we talking about here? Americans? Europeans? What age range? How can that number be so high? Salt has plenty of iodine in it.



#8 xls

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Posted 06 February 2015 - 03:23 AM

Remember to supplement with selenium if you're dosing iodine, esp in large amounts.
http://www.lef.org/p...ulation/Page-08

"Without adequate selenium, high iodine levels lead to destruction of the thyroid gland cells.121,122"

http://www.ncbi.nlm....pubmed/16943608

 

Also IIRC kelp has bromide which iodine seeks to get rid of...IDK though look into that one yourself. There's a huge iodine/iodide thread here: http://www.longecity...ted-supplement/



#9 xls

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Posted 06 February 2015 - 03:37 AM

Which 74% of adults are we talking about here? Americans? Europeans? What age range? How can that number be so high? Salt has plenty of iodine in it.

 

 

Yeah, um...source!?? Don't just say things like that without backing it up.
This is a really good read: http://pubs.acs.org/....1021/es0719071

 

Esp notice the "How Much Iodine Do We Get from Salt? The Iodine Gap" section.
Getting optimal  salt intake from salt with optimal iodine content
everyday gives you 45 µg...recommended iodine intake is ~150ug daily.

Then they go on,

"...only one-fifth of the salt consumed in the United States is iodized". So the average person gets even less from salt.

 

*VERY INTERESTING THING TO NOTE*: "Japan is one of the few countries where salt is not iodized because the Japanese diet contains large amounts of iodine-rich seaweed (57). One study reported the average urinary excretions in Japan to range between 700 and 3200 µg/d (58); this is considerably over what U.S. doctrine would regard as the maximum safe level. Nevertheless, thyroid health in Japan is excellent; there is no excess incidence of autoimmune thyroiditis that supposedly results from excess iodine consumption."

 

http://pubs.acs.org/....1021/es0719071
 



#10 Plasticperson

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Posted 06 February 2015 - 04:17 AM

interesting the days i use kelp salt i definitely feel more energy. been using low sodium kelp salt for about a month now and i really think it does help the thyroid which in turn provides more energy


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#11 normalizing

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Posted 06 February 2015 - 07:04 PM

you mean you been eating kelp? what the hell is kelp salt?


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#12 Plasticperson

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Posted 07 February 2015 - 02:10 AM

you mean you been eating kelp? what the hell is kelp salt?

 low sodium kelp granules.. i put it in grits 


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#13 normalizing

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Posted 07 February 2015 - 09:50 AM

why not eat kelp?


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