Niacin limits the progression of Alzheimer's disease

I don't really want to take this off topic, but I was under the impression that niacin was a very beneficial nutrient and worth taking as a supplement. It seems most of the research bears this out, as you posted above, however,

I just came across this research that claims excess niacin is bad for your heart. I guess the "dose makes the poison"? Maybe. Considering that most medical and health research is not reproducible (well-proven), maybe this is a poor or misinterpreted negative result from analyzing niacin usage, considering the voluminous positive research that is in contrast. 

I think they found this metabolite of high niacin in blood tests, mainly by niacin supplementers. Most often already with CVD, they are of course at higher risks than non-supplementers.

I don't really want to take this off topic, but I was under the impression that niacin was a very beneficial nutrient and worth taking as a supplement. It seems most of the research bears this out, as you posted above, however,

 

I just came across this research that claims excess niacin is bad for your heart. I guess the "dose makes the poison"? Maybe. Considering that most medical and health research is not reproducible (well-proven), maybe this is a poor or misinterpreted negative result from analyzing niacin usage, considering the voluminous positive research that is in contrast. 

It could be just a Big Pharma "study" to get people to carry on taking statins.

It could be just a Big Pharma "study" to get people to carry on taking statins.

Great point. This has happened with many other diseases and drugs - big pharma influencing the results of studies. It would be worth investigating the conflicts of interest.