3 replies to this topic

[Qowpel]

So I am doing calorie restriction at roughly 20% restriction. My total methionine intake is roughly 3 grams per day at a total of 70 grams of protein per day and 1200 total calories. (I am 145 pounds).

 

Is this too much methionine?

[Darryl]

The requirement is 10 mg/kg, so a 145 lb=65.7 kg person only needs 657 mg. Ie, your methionine intake is ~4.5 times the requirement.

 

On average, Americans appear to get around 3 times as much methionine as required, but high protein intake and high methionine protein sources like eggs can send it higher. Its difficult to design a varied whole foods diet that would be deficient in methionine, even vegans typically get 1.5 times the requirement.

 

If you're using protein to suppress appetite, you may want to look at protein sources with a higher leucine/methionine ratio (leucine being the key AA in appetite suppression). Legumes have Leu/Met ratios of 6-9, whereas dairy is ~3.9, animal flesh (any) is 2.8-3.4 and eggs are only 2.3. One reason I think fava beans (9.2) may be the best protein source. Or you could supplement with gelatin or glycine, as there's some evidence glycine may help clear excess methionine.

 

 

Edited by Darryl, 16 February 2015 - 05:30 AM.

[Qowpel]

The requirement is 10 mg/kg, so a 145 lb=65.7 kg person only needs 657 mg. Ie, your methionine intake is ~4.5 times the requirement.

 

On average, Americans appear to get around 3 times as much methionine as required, but high protein intake and high methionine protein sources like eggs can send it higher. Its difficult to design a varied whole foods diet that would be deficient in methionine, even vegans typically get 1.5 times the requirement.

 

If you're using protein to suppress appetite, you may want to look at protein sources with a higher leucine/methionine ratio (leucine being the key AA in appetite suppression). Legumes have Leu/Met ratios of 6-9, whereas dairy is ~3.9, animal flesh (any) is 2.8-3.4 and eggs are only 2.3. One reason I think fava beans (9.2) may be the best protein source. Or you could supplement with gelatin or glycine, as there's some evidence glycine may help clear excess methionine.

well speak of the devil lol I am supplementing with gelatin at 10 grams per day and on the back of the bottle it says in one serving 1 gram is from methionine. So the other part of my diet simply contributes roughly another 1.9 grams from straight food. What do you think?

[Darryl]

Gelatin is 0.7% methionine, so you're at most getting 70 mg from 10 g.