Very nice work at the cross-road of physics and genetics:
http://www.medicalne...ases/304536.php
from the study:
"The NIR optoporation
method will eliminate the requirement for multiple virus delivery and
the possible immunogenic reactions, as well as offering the ability to
deliver macro-constructs encoding opsins that are sensitive to a broad
spectral range to spatially targeted areas of retinal degeneration. Such
spatially resolved delivery of genes to the peripheral retina/macula is
ideal for sensitizing retinal areas that have degenerated, thus paving
the way toward restoring lost vision in RP/AMD patients."
The study is free at:
http://www.nature.com/lsa/latest.html
"Optogenetics: laser-based targeted delivery of genes"
by Kamal Dhakal, Subrata Batabyal, Weldon Wright, Young-tae Kim and Samarendra Mohanty
