2318 replies to this topic

[SenBen]

Thank you very much Kelvin!

 

You really helped me.

 

Just one more question and I will not bother you again:

 

On Fission (day 1) - 1 gram Nicotinamide 

Do I have to take also 1g of Ribose or 1 gram Nicotinamide is enough?

 

Thank you!

 

[Kelvin]

Thank you very much Kelvin!

 

You really helped me.

 

Just one more question and I will not bother you again:

 

On Fission (day 1) - 1 gram Nicotinamide 

Do I have to take also 1g of Ribose or 1 gram Nicotinamide is enough?

 

Thank you!

 

That's easy:  Save your time and money and skip the ribose.  

 

You don't need it for the protocol.

Edited by Kelvin, 30 April 2025 - 12:10 AM.

[SenBen]

Thank you Kelvin!

[SenBen]

Could anyone please tell me if

Nicotinamide is the some as Niacinamide?

 

I need Nicotinamide for Mito protocol.

 

 

Thank you!

[stephen_b]

Could anyone please tell me if

Nicotinamide is the some as Niacinamide?

 

I need Nicotinamide for Mito protocol.

 

 

Thank you!

 

Yes it is.

 

Nicotinamide and niacinamide are two names for the same compound, a form of vitamin B3. They are chemically identical and have the same functions. Niacinamide is more commonly used in the skincare industry, while nicotinamide is the scientific name, often used in research and supplements. 

(google)

[SenBen]

Thank you!

[Alessandro]

Now is there KL-1333, the first-in-class for NAD+.

The only one able to rescue people with primary mitochodrial diseases.

[ekaitz]

Remember to alternate between NMN and Nicotinamide for fission on SEPARATE days because although NMN causes fission in most of the body it causes fusion in the brain, while nicotinamide/NAM causes fission in the brain.  If you take nicotinamide at the same time as NMN they cancel each other out for no brain benefit.

 

So do this

 

Fission (day 1) - 1 gram Nicotinamide 

Fusion (day 2) - (AAKG is not necessary on fusion day if taking 1 gram of AKG - I use Double wood brand AKG)

Fission (day 3) - 1 gram NMN

Fusion (day 4) - normal fusion stack

Fission (day 5) - 1 gram Nicotinamide 

etc, etc

 

Yes you can take TMG.

I usually take 2 grams TMG every 3- 4 mito cycles to restore methyl stores that are depleted by NMN and NAM.

 

Is it ok to use NR instead NMN for the same benefit? Same amount, 1gram?

 

Also, shouldn't PQQ be added on fusion days along with the AKG?
 

Edited by ekaitz, 31 August 2025 - 11:10 PM.

[Kelvin]

Is it ok to use NR instead NMN for the same benefit? Same amount, 1gram?

 

Also, shouldn't PQQ be added on fusion days along with the AKG?
 

 

 

Nicotinamide and NMN appear to have different effects.

 

Both I and others have noticed greater muscle tone when using NMN for fission relative to nicotinamide.  NMN also has other benefits that nicotinamide does not such as improving insulin sensitivity in diabetics and prediabetics.

 

Since they have different affects, they probably affect mitochondria differently and so I rotate them on fission days just to be sure I am affecting as much mitochondria as possible.

 

Dosage is 1 gram nicotinamide (since using more than that doesn't appear to improve results) and at least 750 mgs of NMN, sometimes 1 gram NMN.

 

For PQQ I don't think it is necessary to use it more than 1 every 4 fission cycles to eliminate stray epigenetically damaged mitochondria that escaped the fission protocol days that didn't use PQQ.  

 

I don't use it more because (based on Turnbuckle's description of mitochondrial latching) PQQ increases mitochondrial numbers and, since the C60 protocol works by affecting mitochondrial morphology, I don't want excessive PQQ use to potentially negatively affect the C60 protocol when I use it.

 

I forget the reason Turnbuckle used PQQ on fusion days, but I haven't noticed any improvement when using it on fusion.  So I just use PQQ on fission days, and this seems to work just fine.

Edited by Kelvin, Today, 08:47 PM.