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What to take for life extension? Your top list

life extension niagen supplement research longelivity

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#31 Rocket

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Posted 06 June 2017 - 01:06 AM

Niacin (couple grams)
Garlic
A quality Whey protein
Raw egg
Aspirin
Tudca acid
Walnuts
Iodine
Planning on adding in c60 olive oil soon
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#32 Benko

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Posted 06 June 2017 - 02:33 PM

Metformin is frequently recommended but a number of people don't feel well taking it.   Another compound which also raises AMPK is the Chinese herb gymnostemma.  It also has positive effects of insulin sensitivity, etc.  Good info on it at examine.com but I don't seem to be able to paste the link.

 

 

 


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#33 Benko

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Posted 06 June 2017 - 02:37 PM

Metformin is frequently recommended, however a number of people don't feel well taking it.  The Chinese herb gymnostemma also works via AMPK and also has positive effects of insulin sensitivity.  Lots of good info on it at examine.com.


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#34 AceNZ

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Posted 19 September 2017 - 03:19 AM

Key factors:

Insulin sensitivity and blood glucose

Mitochondrial health

Brain health

Detoxification

Support or replace key hormones (cortisol, DHEA, testosterone, thyroid)

Address genetic weak spots, such as MTHFR

Watch for copper vs. zinc imbalance and treat as needed

Eliminate heavy metals everywhere

 

Resveratrol

Niagen

Niacin

RG3 Ginseng

Vit A

Good B-complex (I take B-Right)

Vit C

Vit D3

Vit E + tocopherols (all 8 forms)

Vit K2 (limits calcification)

Good Multi-mineral (I take PicMins)

Healthy fats (avoid polyunsaturated oils like the plague)

Acetyl-L-Carnitine

Magnesium

Melatonin (esp. over 50)


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#35 Rossi

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Posted 25 September 2017 - 03:31 PM

1. Exercise following the Biologic Revelation protocols. (www.biologicrevelation.com)

2. One capsule a day of the Two a Day Life Extension Multivitamin.

3. Optimized Resveratrol with Nicotinamide Riboside (New Life Extension Formula)

4. 12 mg of Viagra every few days.

5. Careful lower calorie diet leaning toward pesco vegetarianism.

 

Waiting for a senolytic drug to be available.

 


Edited by Rossi, 25 September 2017 - 04:20 PM.

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#36 Multivitz

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Posted 28 September 2017 - 11:17 AM

I've tried and taken everything anyone could mention! A bold statement, I know, it would be easier to list what things I haven't tried!
Boron and iodine are the key minerals that get the body recatalised and able to do the things it needs to heal. Discover what YOUR body needs as companion nutrients. Never take drugs, the synthetic types. Try not to take synthetic vitamins. Research Aceytlation/Methalation in the body. Vanadium, molybdenum, zinc, magnesium are essential, but copper selenium, calcium and iron are the ones that can be abundant, so show caution. Globular proteins should be taken sparingly. Exercise until moderate pain and be progressive if possible.
Use quarter dosing, only use mega dosing after familiarising yourself with deficiency symptoms of other nutrients involved with the pathways. If in doubt, leave it out. Or experiment with yourself.
Anxiety is a detachment, or blockage of the nerve from the flesh. Just a random fact. Thx
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#37 Captain Obvious

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Posted 27 February 2018 - 07:02 PM

IP6 (Inositol Hexaphosphate)

Glucosamine

Niacinamide (also NR at the moment, but not sure it's any better)
Niacin

LEF Cruciferous Vegetable Extract

Olive Leaf Extract

Green Tea Extract

LEF Two-Per-Day (half dose)

LEF Only trace minerals

Beta-alanine
Lithium Ororate
Baby Aspirin
Melatonin

Gamma-linolenic acid (GLA) + Ashwagandha (based on the Geroprotect supplement by LEF)

Vitamin D + K w/ iodine

Berberine + Curcumin with Bioperine and Milk Thistle to increase bio-availability

EPA / DHA


Edited by Captain Obvious, 27 February 2018 - 07:20 PM.

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#38 Rossi

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Posted 27 February 2018 - 07:12 PM

1. Exercise following the Biologic Revelation protocols. (www.biologicrevelation.com)

2. Both capsules each day of the Two a Day Life Extension Multivitamin.                      (This is a change from above)

3. Optimized NAD+ Cell Regenerator with Resveratrol                                                 (This is a change from above)

4. 12 mg of Viagra every few days.

5. Plant-based diet without oils or nuts.                                                                        (This is a change from above)

6. 1000 mg Vitamin C.                                                                                                 (This is an addition to above)

 

Waiting for a senolytic drug to be available.


Edited by Rossi, 27 February 2018 - 07:14 PM.

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#39 VP.

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Posted 27 February 2018 - 07:59 PM

What is really needed is a set of test that predict our biological age. Without that how in world are you going to know if anything is working? Maybe this is part of the answer. 

Simple urine test could measure how much our body has aged A promising new marker of aging could help predict the risk of developing age-related disease and even death

https://www.scienced...80227090733.htm

 

 


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#40 Sith

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Posted 28 February 2018 - 02:06 PM

Longevity:

  1. 2 x 500mg Metformin.
  2. 20,000IU Vitamin D3.
  3. 1000mg Resveratrol with piperine. 
  4. 15mg Astaxanthin. 
  5. 500mcg Vitamin K2/MK7.
  6. 15-20g Astragalus root. 

This is all taken in combination with a Mcdougall syle vegan diet, some further 'dietary' supplements for general health are:

  • Vitamin B complex.
  • Milled flaxseed.
  • Amla powder.
  • 1000mg Vitamin C.

 

And unfortunately... 1mg of Finasteride. Absolutely no side effects, thankfully.

 

Details:

Male, early 20s.

 

 


Edited by Sith, 28 February 2018 - 02:07 PM.

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#41 Believer

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Posted 28 February 2018 - 11:48 PM

And unfortunately... 1mg of Finasteride. Absolutely no side effects, thankfully.

 

Details:

Male, early 20s.

 

Why finansteride?
 


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#42 Captain Obvious

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Posted 01 March 2018 - 02:51 PM

Someone was "unsure" about my "stack". I would be happy to answer questions and would be even happier to drop/replace any useless supplements, but just clicking "unsure" seems a bit unproductive. :)


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#43 tintinet

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Posted 01 March 2018 - 07:28 PM

Broccoli sprouts, curry with curcumin and turmeric, garlic, blueberries, strawberries, goji berries, yoga, weight lifting, aerobic exercise, intermittent fasting...

 

and pterostiobene, melatonin, rifampin, aspirin, NMN, and Lactobacillus reuteri.

 

I've taken C60EVOO, mitoq, CoQ10, ALA, carnosine, beta-alanine, NAG, NAC, ALT-711, ad infinitum, for periods, and cycle through many things intermittently.  Northing seems to stay in favor for long, though. 



#44 Sith

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Posted 02 March 2018 - 02:26 AM

 

And unfortunately... 1mg of Finasteride. Absolutely no side effects, thankfully.

 

Details:

Male, early 20s.

 

Why finansteride?
 

 

 

To stave off the hair loss!

 

Also... Someone was unsure on my regimen as well. Please feel free to critique.


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#45 Andrews

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Posted 03 March 2018 - 07:11 PM

Niagen 250mg ( 250mg 30 minutes before breakfast )

Trans Pterostilbene

Trans Resveratrol

Broccomax

Krill Oil

Piperine (for better absorption)

BioAstin 12mg (astaxanthin)

Probiota Histaminx

 

And other less important like;

Nigella Sativa oil

Coleus Forskohli

Rhodiola Rosea

Tribulus Terrestris

Lipidium Meyeni

 

Fresh healthy food. (Gluten free and low dose histamine diet).

 

What do you think about this?

Im thinking about C60 in olive oil.

 

 

 

 


Edited by Andrews, 03 March 2018 - 08:01 PM.


#46 Andrews

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Posted 04 March 2018 - 08:47 AM

Niagen 250mg ( 250mg 30 minutes before breakfast )

Trans Pterostilbene

Trans Resveratrol

Broccomax

Krill Oil

Piperine (for better absorption)

BioAstin 12mg (astaxanthin)

Probiota Histaminx

 

And other less important like;

Nigella Sativa oil

Coleus Forskohli

Rhodiola Rosea

Tribulus Terrestris

Lipidium Meyeni

 

Fresh healthy food. (Gluten free and low dose histamine diet).

 

What do you think about this?

Im thinking about C60 in olive oil.

Spirulina also and no alcohol and coffee.

 

 


Edited by Andrews, 04 March 2018 - 08:48 AM.


#47 aribadabar

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Posted 05 March 2018 - 08:50 PM

Niagen 250mg ( 250mg 30 minutes before breakfast )

Trans Pterostilbene

Trans Resveratrol

Broccomax

Krill Oil

Piperine (for better absorption)

BioAstin 12mg (astaxanthin)

Probiota Histaminx

 

And other less important like;

Nigella Sativa oil

 

 

I'd say NS oil is more important than most of the names above.


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#48 Skyguy2005

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Posted 06 March 2018 - 03:28 AM

Category 1: Sirolimus. Weird.

Category 2: Ginkgo Biloba, Salicin, Reishi, Resveratrol. Less effective but normal.


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#49 ledgf

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Posted 07 March 2018 - 05:37 PM

Tru niagen 250 mg (assuming that you're over 50)

A good telomerase activator (if we can get one)... otherwise, you might have to Liz Parrish yourself with AAV vector telomerase

And pay up your cryonics insurance

But the best anti-aging medicine would be a country where biotech was fully legal... if terminal patients were allowed to try experimental drugs, then biotech would progress as fast as computers. Our little cell-computers only have 2.8 gig of memory, and 97% of that is just "malware" (old lentivirus)  ;)

http://www.concordmo...naires-13878920

 


'I knew LEDGF P75, and you, sir, are definitely mostly lentivirus" ;)

https://www.ncbi.nlm...pubmed/16959972


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#50 samotaki

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Posted 23 October 2018 - 01:30 PM

Bioflavonoids

L Carnosine (Karnozin Extra)

Vitamin C

 


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#51 baccheion

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Posted 28 October 2018 - 11:18 AM

Iodine protocol
Vitamin K2 MK-4 (+ vitamin D3; 2 mcg+ : 10 IU)
Selegiline

#52 John250

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Posted 28 October 2018 - 08:04 PM

TruNiagen
Cycloastragenol
Astragaloside iv 20%
MitoQ
idebenone
Aspirin
Metformin
PQQ
Vitamin D
Resveratrol
UltraCur Curcumin
Lions Mane
EPA/DHA
NA-R-ALA
Fisetin
NAC
Astaxanthin
CDP Choline
Indole-3-Carbinol
Pycnogenol
Magnesium
7,8 DHF
Chocamine
Pomella
S-Acetyl-L-Glutathione
Humanofort

Edited by John250, 28 October 2018 - 08:11 PM.

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#53 Soalian

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Posted 29 October 2018 - 04:58 PM

TruNiagen
Cycloastragenol
Astragaloside iv 20%
MitoQ
idebenone
Aspirin
Metformin
PQQ
Vitamin D
Resveratrol
UltraCur Curcumin
Lions Mane
EPA/DHA
NA-R-ALA
Fisetin
NAC
Astaxanthin
CDP Choline
Indole-3-Carbinol
Pycnogenol
Magnesium
7,8 DHF
Chocamine
Pomella
S-Acetyl-L-Glutathione
Humanofort

Wow, how much are you actually taking at once/daily? Regarding Pomella, I already take some Pomegranate extract derived from the dried fruit, allegedly standardized to 40% Ellagic Acid (Didn't test it), I've been considering switching to a proven formulation such as ND's Pomella since I'm interested in the benefits of Urolithin A, what's your experience with it?

 



#54 John250

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Posted 29 October 2018 - 08:28 PM

Wow, how much are you actually taking at once/daily? Regarding Pomella, I already take some Pomegranate extract derived from the dried fruit, allegedly standardized to 40% Ellagic Acid (Didn't test it), I've been considering switching to a proven formulation such as ND's Pomella since I'm interested in the benefits of Urolithin A, what's your experience with it?


I never really notice anything from supplements I just used him for health preventives. That’s list is nothing though lol

https://www.longecit...lement-arsenal/

#55 Rossi

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Posted 29 October 2018 - 11:54 PM

1. Exercise following the Biologic Revelation protocols. (www.biologicrevelation.com)

2. One capsule a day of the Two a Day Life Extension Multivitamin.

3. Optimized Resveratrol with Nicotinamide Riboside (New Life Extension Formula)

4. 12 mg of Viagra every few days.

5. Careful lower calorie diet leaning toward pesco vegetarianism.

 

Waiting for a senolytic drug to be available.

 

Now:

 

Optimized Resveratrol with Nicotinamide Riboside (New Life Extension Formula): 

 

NIAGEN 250 mg.

Quercetin 150 mg.

Trans-Resveratrol 100 mg.

Red grape (fruit) and wild blueberry (fruit) blend (providing polyphenols, anthocyanins, OPCs) 40 mg.

Fisetin 10mg. 

 

Vegan

 

Moderate stretching and exercise, aerobic and anaerobic.

 

 

Waiting for a senolytic drug to be available.


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#56 brosci

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Posted 30 October 2018 - 10:50 PM

  • Omega-3 (phospholipid form)
  • Magnesium (reacted / chelated form)
  • B-Complex (methylated / active form)
  • K2 (Mk4 + Mk7)
  • Iodine
  • D3
  • Creatine (monohydrate)
  • Amino acids (peri-workout)
  • Adaptogen (cycle)
  • Polyphenol / Phytonutrient (cycle)
  • Vitamin C
  • Zinc (low-dose)

That's sort of my go to.  The adaptogens / phytos are where things look interesting on a month to month basis, with stuff like resveratrol, pterostilbene, fisetin, curcumin, reishi, lions mane, etc.


Edited by brosci, 30 October 2018 - 10:51 PM.


#57 baccheion

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Posted 31 October 2018 - 05:57 AM

  • Omega-3 (phospholipid form)
  • Magnesium (reacted / chelated form)
  • B-Complex (methylated / active form)
  • K2 (Mk4 + Mk7)
  • Iodine
  • D3
  • Creatine (monohydrate)
  • Amino acids (peri-workout)
  • Adaptogen (cycle)
  • Polyphenol / Phytonutrient (cycle)
  • Vitamin C
  • Zinc (low-dose)

That's sort of my go to. The adaptogens / phytos are where things look interesting on a month to month basis, with stuff like resveratrol, pterostilbene, fisetin, curcumin, reishi, lions mane, etc.</p>
How much iodine do you take?

#58 brosci

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Posted 31 October 2018 - 06:02 AM

How much iodine do you take?

 

I ramped up over the course of a year from 100mcg/d to north of 1mg/d (along with selenium), then ramped back down, feeling like I fairly adequately saturated with the stuff.  My thyroid levels are all decent and antibodies are undetectable, so everything went well.  I now just do 200-300mcg/d as a maintenance dose.  I've tried nascent iodine, but I hate the taste.  Potassium iodide is basically water by comparison.  Personally, I don't feel the need to go higher than the 2-3 drops I currently take.



#59 dazed1

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Posted 18 January 2019 - 03:09 AM

For heart disease, energy levels, preventing and reversing gray hair, skin quality and basically everything in your body, high dose nicotinic acid + l-carnitine is a very effective combo

For cancer prevention Selenium complex (Life-Extension brand) is good.

 

Vitamin C, lysine and vitamin k2 are also incredibly good for various aspects of heart disease.

 

This is plain wrong, high dose nicotinic acid, sends BG into double numbers for insulin resistant, and diabetic individuals.

 

On,

 

1. Kyolic Garlic

2. Ubiquinol

3. Fish oil 4g/day

4. Sulbutiamine/Benfotiamine + Methylcobalamin + P5P + Myoinositol + Methylfolate

5. Taurine

6. D3/K2 MK4

7. Berberine

8. Na-R.ala

9. Resveratrol

10. Gamma T  + Tocotrienols

11. OLE

12. Magnesium

13. Methylselenocysteine

14. Rutin + citrus bioflavonoids

15. Rosemary/Turmeric/Ginger/Cloves/Mexican Oregano/Black Seed/Spearmint


Edited by dazed1, 18 January 2019 - 03:20 AM.

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#60 AceNZ

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Posted 18 January 2019 - 10:06 PM

IP6 (Inositol Hexaphosphate)

Glucosamine

Niacinamide (also NR at the moment, but not sure it's any better)
Niacin

LEF Cruciferous Vegetable Extract

Olive Leaf Extract

Green Tea Extract

LEF Two-Per-Day (half dose)

LEF Only trace minerals

Beta-alanine
Lithium Ororate
Baby Aspirin
Melatonin

Gamma-linolenic acid (GLA) + Ashwagandha (based on the Geroprotect supplement by LEF)

Vitamin D + K w/ iodine

Berberine + Curcumin with Bioperine and Milk Thistle to increase bio-availability

EPA / DHA

 

In case you didn't already know, IP6 (also known as phytate) is a chelating agent, and is particularly known for absorbing Zinc, but also Manganese, Magnesium, Copper and others. Personally, I wouldn't take it for the long term for that reason, but if you do, then added Zinc supplementation and periodic blood tests (serum Zinc is fine) would be advisable.







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