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Anyone tried cannabidiol (CBD)?

cannabidiol cannabis cbd cb2

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409 replies to this topic

#151 Al Capacino

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Posted 28 May 2014 - 05:53 PM

Nice digging Mr.Nootropic.
After typing that address into Google and finding the exact number of the property on streetview it shows a terraced house with a sign outside to rent.

I also second what you say about "customer reviews" as being useless as anyone can make that stuff up. Just marketing speel.
When it comes to buying and selling medicinal substances people want facts and to know that what they are buying is as described, know where the ingredients have come from and is safe.

I am reluctant to buy again Tbh after seeing where the product is made. In a terraced rented property by the looks of it.
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#152 mrnootropic

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Posted 28 May 2014 - 08:57 PM

Nice digging Mr.Nootropic.
After typing that address into Google and finding the exact number of the property on streetview it shows a terraced house with a sign outside to rent.

I also second what you say about "customer reviews" as being useless as anyone can make that stuff up. Just marketing speel.
When it comes to buying and selling medicinal substances people want facts and to know that what they are buying is as described, know where the ingredients have come from and is safe.

I am reluctant to buy again Tbh after seeing where the product is made. In a terraced rented property by the looks of it.

 

I am reluctant to buy anything from Medivape..

 

However, if they prove themselves, i will fully support them..

Anyone trying to promote CBD  in the uk that is Professional and Legitimate, i will support.

 

But Medivape doesnt seem legit or Professional, yet.

As soon as they become more transparent, i will definitely buy some and continue to support them,

 

However right now, there are too many unanswered questions and i don't even know what kind of enviroment the CBD Oil is made in.

 

As soon as Cbdbro becomes transparent, i will support him..


Edited by Mr.Nootropic, 28 May 2014 - 08:58 PM.

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#153 cbdbro

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Posted 28 May 2014 - 11:19 PM

Jeese people why don't we try to bring an end to the only company providing CBD products in the UK. Obviously as a 'grey area' one does not want the wrong people looking in the right places or its over before it starts i can assure you we do not operate from a terraced house up for rent. All i can say at this point is ask a man named Jeff Ditchfield about the guy who runs Medivape, he is as trusted as it comes and after 2 hours of grilling on skype and pushing for the tincture to be tested in the lab way back in October he decided unequivocally we were legit. Google him it doesn't get much bigger than Jeff...


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#154 YoungSchizo

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Posted 25 June 2014 - 01:52 PM

After reading many schizophrenics that have had success treating their schizophrenia with CBD and reading these articles I'm persuaded to try CBD in the near future.

 

I haven't read the topic so excuse me if this already has been asked, how and where do I get a, cheap, high dosed, non-THC, CBD extract and/or consumable oil-drops. Like those high CBD strains that are only produced in the USA? I'm actually not looking for a strain because I suck at gardening, (though I might grow strains in the future if CBD really helps me because it's legal in the Netherlands to grow 4 cannabis plants at home and CBD isn't considered drugs anyway). So I'm not looking for Cibdex and/or Pixie's that are low in CBD and are to pricey but am looking for a cheap reliable source that sell high dosed CBD product (maybe I can put CBD in my e-cig and vape it).

 

Hope someone can help me out, who knows, maybe I can stop taking benzo's and antipsychotics and replace it with a natural CBD-therapy.

 

 



#155 Flex

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Posted 25 June 2014 - 05:40 PM

Cant help You. the only things are medivape that is seemingly down, the Industrial hemp buds (as posted) and maybe the flax seed -.-

 



#156 shantaram

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Posted 27 June 2014 - 05:35 PM

There are only the "expensive" brands, I think 230mg for ~30€ is the cheapest I could find. But that stuff is not smokeable I think, as they dilute it with some oil. There is also e-liquid, but it's not that cheap with 50mg for ~33euro.

I tried to look up the bioavailability of sublingual CBD, don't think it has been tested in humans. Smoked, it is about 30%.


Edited by shantaram, 27 June 2014 - 05:38 PM.


#157 mrnootropic

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Posted 01 July 2014 - 04:08 PM

Jeese people why don't we try to bring an end to the only company providing CBD products in the UK. Obviously as a 'grey area' one does not want the wrong people looking in the right places or its over before it starts i can assure you we do not operate from a terraced house up for rent. All i can say at this point is ask a man named Jeff Ditchfield about the guy who runs Medivape, he is as trusted as it comes and after 2 hours of grilling on skype and pushing for the tincture to be tested in the lab way back in October he decided unequivocally we were legit. Google him it doesn't get much bigger than Jeff...

 

Hey Cbdbro, your website is down ?

Are you updating your website or switching domain names ??

 

Im not trying to bring an end to your business, im trying to tell you that you need to tell us how your CBD oil is made. It could be Snake Oil with 0% CBD in. You are operating from an Housing Estate, or your business is based there.

 

I own a web hosting company, web designs and brand building companies so i can help you with web hosting and your website design. 

 

Im not trying to put an end to anything Cbdbro, im trying to help you.

You have to be transparent and honest with your customers. You should want to tell people how your product is made. This is Business 101, if your customers dont trust you or your website , then your bounce rate is going to be high.

 

Clearing up all grey areas in your business, will attract more potential customers and reduce bounce rates.

I seriously dont understand your business model. If you dont want people to copy then why not get a patent?

Like i said i can help. I can help with SEO, Hosting, Design, Maintenance and Brand Reputation and alot more.

 

And i repeat : Im not trying to bring an end to your business, im trying to do the opposite and help you.

 

I also want to try CBD Oil, which is why i was so concerned about how it was made. I wish Cannabis was legal in the UK and i wish CBD was available in Chemists. But this is not the case. 

I want the see any CBD company in the UK flourish and have success.


Edited by Mr.Nootropic, 01 July 2014 - 04:19 PM.


#158 cbdbro

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Posted 18 July 2014 - 03:38 PM

Not trying to bring an end to it by digging to try and find where medivape is run from and then posting it to the web for anyone including authorities, to see. The tincture was tested in a lab at the request of an anti scammer site. they decided i was genuine and the lab test secured it as i said befiore - jeff ditchfield will tell you. If you dont believe in HPLC testing that doesnt suprise me in the slightest - people like yourself take nothing as a good enough answer or proof. The tincture is made from locally sourced hemp from a farmer who previously supplied GW pharma but stopped as the transport distance was not cost effective. Said hemp is grown organically without pesticides and is also sold abroad for use in hemp tea bags in Holland. Said hemp has a lab tested (by GW) cannabinoid count of 6% CBD and 4% THC. Said hemp would be cooked low for a long period of time with veg glycerin food grade and then de-carboxilated. Its trade secrets your prying for so understandably i was reluctant, why dont you go and pester GW pharmaceuticals for their methods im sure they know far more and they are a big company not a guy on his own trying to make a difference in this suspicious world



#159 Flex

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Posted 18 July 2014 - 08:06 PM

@ cbdbro

 

Could You post the homepage of medivape ?

I cant find it



#160 YoungSchizo

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Posted 19 July 2014 - 11:10 AM

@ cbdbro

 

Could You post the homepage of medivape ?

I cant find it

 

I got send to this site when I was looking to buy from medivape.

 

This one is new, though, at the suggested usage it says 1g per day..? Am I not seeing this right or are they friggin kidding me, the tube ($159,-) contains only 3 grams.  


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#161 Flex

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Posted 19 July 2014 - 03:49 PM

Thanks for the response.

Seems that Medivape is Down.

 

No, its worser -.-

They want 435mg CBD for 160$...

 

Btw:

There is also another interresting ingredient in Cannabis apart from CBD named Cannabichromene (CBC).

http://en.wikipedia....Cannabichromene

 

http://www.leafscien...bichromene-cbc/

 

The effect of cannabichromene on adult neural stem/progenitor cells.

http://www.ncbi.nlm....pubmed/23941747

 

It occurs seemingly in Rhododendron anthopogonoides

 

New cannabinoid-like chromane and chromene derivatives from Rhododendron anthopogonoides.

http://www.ncbi.nlm....pubmed/22041081


Edited by Flex, 19 July 2014 - 04:02 PM.


#162 YoungSchizo

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Posted 20 July 2014 - 12:23 PM

I think isolating and researching only CBC will take some time..

 

I wonder why it's so hard and expensive to isolate and sell high dosed CBD.. I mean, they know how to extract/isolate it, they sell high dosed CBD strains already but on the international CBD market it's still too expensive and impossible (at least, for me) to use it (maybe permanently) in my stack.

 

Btw. in the link you gave it claims CBC and CBD work as pain relievers for the spine, that's great to hear, my back is killing me!!


Edited by YoungSchizo, 20 July 2014 - 12:27 PM.


#163 Flex

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Posted 24 July 2014 - 04:02 PM

YoungSchizo

Glad to Help :-)

 

I found out that Magnolia officialis has a compound, ( tetrahydromagnolol ) that inhibit the GPR55 receptor like as CBD does it.

See my Topic:

http://www.longecity...ts/#entry676786

 

Hopefully this helps to get rid of those excessive prices for CBD..


Edited by Flex, 24 July 2014 - 04:03 PM.

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#164 Forty Six & 2

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Posted 24 July 2014 - 06:10 PM

Hey Flex,

 

Good find, but we at TrueLIFE Research (TeamTLR) have looked into this extensively, within our program for Optimized Cannabinergic Modulation Research.  This is a part of our Optimization Research program that we have placed great emphasis upon for several years.  

 

This particular compound is exceptionally weak as to GPR55 modulation within regards to its inherent potency and oral bioavailability as per our in vitro and in vivo assays performed.  As such, its practicality as a viable means for such modulation is extremely limited.  Its only remotely practical application is as a selective weak partial agonist of CBR2, which really does not have much merit within the scope of the desired 'CBD-mimetic' desired activity, and our determination as well showed quite weak partial agonist activity.  There are far better agents to be pursued within the scope of all such related research.  

 

Notably, we have a CBD-mimetic we have been working towards optimizing for quite some time and it should hopefully reach fruition shortly.

Look under the category "Cannabinergics" on the site for more on our cannabinergics.

 

We have also developed a strain of hemp that is high in CBD and are pursuing making highest quality, reasonably priced CBD extracts available shortly.  Again, we have worked within this area for many years and have a passion for the promise of research into well-directed cannabinergic modulation.

 

Note as well, we have a CB1 partial agonist extract that is highly suited for research into pursuing optimized CBR1 modulation with highest therapeutic indices.

 

Cheers!


Edited by Forty Six & 2, 24 July 2014 - 06:11 PM.


#165 Flex

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Posted 24 July 2014 - 06:39 PM

Thanks for the Response.

Yes, the magnolia compund is very weak (13,000 nM).

In the case that this compound is obtainable and cheap.

, it would be perhaps still worth a try.

 

Your shop is very interresting for me, I wish there would be more shops like Yours.

But the compond that You´ve mentioned seems to be expensive, unless low doses are needed.

And I hope that this is not a research chemical, because they could bear some unknown side effect.

 

Unfortunaetly because I live in Germany and I´m not able to order anything outside the EU, 

I´ll have to seek further for those antagonists.

 

 

 


Edited by Flex, 24 July 2014 - 06:44 PM.


#166 YoungSchizo

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Posted 25 July 2014 - 01:04 PM

CBRM-OX

 

90mg for severe pain and mood disorders

 

2g for $55,30 soo that's 22 days dosages, little too expensive for me too..

 

Hope prices will drop more soon.



#167 Flex

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Posted 25 July 2014 - 02:37 PM

Thanks for the Info.



#168 nootz

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Posted 24 September 2014 - 10:09 PM

found this on the fuckcombustion cbd tincture thread, price seems good but I haven't tried it

canibdol from omega labs. I'm wondering if the higher concentrated tinctures produce that mind dulling effect/body load effect, which is precisely why I don't like in herb. I've tried vaping high cbd strains to the same effect despite the dispensary saying it was clear headed.

Is there a mj derived product that is beneficial and truly clear headed as opposed to being clear headed compared to other mj.

 

There is also the raw cannabis juicing as per the youtube video which seems effective, non psychoactive, but a bit hard to procure leaves for


Edited by nootz, 24 September 2014 - 10:19 PM.


#169 Raptor87

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Posted 24 September 2014 - 11:23 PM

found this on the fuckcombustion cbd tincture thread, price seems good but I haven't tried it

canibdol from omega labs. I'm wondering if the higher concentrated tinctures produce that mind dulling effect/body load effect, which is precisely why I don't like in herb. I've tried vaping high cbd strains to the same effect despite the dispensary saying it was clear headed.

Is there a mj derived product that is beneficial and truly clear headed as opposed to being clear headed compared to other mj.

 

There is also the raw cannabis juicing as per the youtube video which seems effective, non psychoactive, but a bit hard to procure leaves for

 

CBD doesn't have any intoxicating effects. Perhaps you need a level of stress to feel optimal and the dulling effects makes you feel drowsy? My stresslevels needs to be high in order for me to function optimally. But perhaps CBD dulls one down? 



#170 nootz

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Posted 25 September 2014 - 12:34 AM

I'm trying to be more positively engaged in novel situations, so I'm seeking a balance of awareness and relaxation, but I found the heaviness to be a bit oppressive both in strength and persistence. It wasn't like having a bottle of beer unless the bottle was broken over your head and knocked you out.



#171 YoungSchizo

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Posted 25 September 2014 - 12:03 PM

I'm trying to buy CBD liquid for my vaporizer from this US based online-store.

 

I don't know if it only counts for international shipping but I can't place an order because they're asking a minimum order of $300,-

Is there anyone in US that has ordered from here and/or is able to order from here individually without them asking a wholesale price? 

 

Edit: I have send them an e-mail if they sell to individuals but have no answer yet. In case it's a no, anyone in for a group buy?

(30ml bottles with 60mg CBD for $14.98 seems a reasonable price and effective dose right?)


Edited by YoungSchizo, 25 September 2014 - 12:10 PM.


#172 nootz

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Posted 25 September 2014 - 09:11 PM

fascinating article on the "entourage effect" of other chemicals in cannabis

 

http://www.alternet....t=13&paging=off
 

once you are comfortable with cbd, you could add in the terpernes using common herbs, or extracts (with proper dilution)

to alter the effects, or to better recreate a full spectrum effect

 

I've heard anecdotal reports about myrcene being trippy/sedating on it's own so I would be careful with that.


Edited by nootz, 25 September 2014 - 09:25 PM.


#173 YoungSchizo

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Posted 28 September 2014 - 08:39 PM

50k views, 172 replies and no one interested in cheap potential CBD liquid..?

#174 Raptor87

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Posted 29 September 2014 - 10:08 AM

50k views, 172 replies and no one interested in cheap potential CBD liquid..?

 

Cheap potential CBD liquid say's it all!



#175 YoungSchizo

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Posted 29 September 2014 - 11:34 AM

The price on the site I mentioned is a whole sale price. If say 20 people buying each 1 to try is reasonable to give this liquid a try, no?



#176 Flex

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Posted 29 September 2014 - 02:00 PM

I will look into.

But if even I agree, I guess it wouldnt be enough for a group buy.

 


Edited by Flex, 29 September 2014 - 02:12 PM.


#177 VERITAS INCORRUPTUS

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Posted 29 September 2014 - 02:16 PM

YS, you may want to seriously re-evaluate what is a good and viable price.  Not sure how one sees  to determine 240usd/gram is a viable and 'cheap' (or even substantially better than current market) price.  

 



#178 KieranA001

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Posted 29 September 2014 - 02:29 PM

mvape.co.uk

 

All I have to say... Good vendor. :-)



#179 Plasticperson

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Posted 29 September 2014 - 05:57 PM

If someone want to try a CB2 agonist and doesn't have access to pure CBD oil...

 

Copaiba Oil contains high quantities of caryophyllene a CB2 agonist that is found in tons of foods. Its an FDA approved flavor additative. High levels are also found in oregano oil. But oregano is extremely nasty and harsh and also has a couple gaba agonists in it. 

 

caryophyllene also doesn't make you test positive for any type of drug test.


Edited by Plasticperson, 29 September 2014 - 05:58 PM.

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#180 Flex

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Posted 29 September 2014 - 08:27 PM

Echinacea too

 

Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.

http://www.ncbi.nlm....pubmed/16547349







Also tagged with one or more of these keywords: cannabidiol, cannabis, cbd, cb2

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