GHK tripeptide resets DNA. Brain, capillar...
Logic
11 Feb 2017
Hi Longecity Friends,
This isn't out of laziness as I've read tons of threads about GHK here and elsewhere
But still can't find the answer to 2 questions I've been asking myself.
- Is GHK with copper dangerous or require super low doses?
The source I found with PAL GHK is expensive (unless doses are low):
https://www.peptides...ces.com/pal-ghk
- Is anyone organizing a Group Buy so that this can become cost effective?
Thanks for your help. I am not looking for a shortcut but need to be set straight on these two issues.
Cheers,
DareDevil
GHK/GHK-Cu group buy?
Interest noted and enquiries made as I too would like to try GHK/GHK-Cu at a reasonable price.
The same procedure of testing by Mass spectrograph will be done on both by the lab, before aliquoting under lab conditions and posting either/both.
I will post more once I have a reply/price.
Rocket
15 Feb 2017
I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
ta5
19 Feb 2017
New article on GHK from Dr. Pickart:
Brain Sci. 2017 Feb 15;7(2). pii: E20.
The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline.
Pickart L1, Vasquez-Soltero JM2, Margolina A3.
Research & Development Department, Skin Biology, WA 98006, USA
Neurodegeneration, the progressive death of neurons, loss of brain function, and cognitive decline is an increasing problem for senior populations. Its causes are poorly understood and therapies are largely ineffective. Neurons, with high energy and oxygen requirements, are especially vulnerable to detrimental factors, including age-related dysregulation of biochemical pathways caused by altered expression of multiple genes. GHK (glycyl-l-histidyl-l-lysine) is a human copper-binding peptide with biological actions that appear to counter aging-associated diseases and conditions. GHK, which declines with age, has health promoting effects on many tissues such as chondrocytes, liver cells and human fibroblasts, improves wound healing and tissue regeneration (skin, hair follicles, stomach and intestinal linings, boney tissue), increases collagen, decorin, angiogenesis, and nerve outgrowth, possesses anti-oxidant, anti-inflammatory, anti-pain and anti-anxiety effects, increases cellular stemness and the secretion of trophic factors by mesenchymal stem cells. Studies using the Broad Institute Connectivity Map show that GHK peptide modulates expression of multiple genes, resetting pathological gene expression patterns back to health. GHK has been recommended as a treatment for metastatic cancer, Chronic Obstructive Lung Disease, inflammation, acute lung injury, activating stem cells, pain, and anxiety. Here, we present GHK's effects on gene expression relevant to the nervous system health and function.
KEYWORDS:
Alzheimer’s disease; DNA repair; GHK; Parkinson’s disease; anti-anxiety; anti-oxidant; anti-pain; copper; dementia; glial cells; neurons
PMID: 28212278
eigenber
19 Feb 2017
Has anyone accessed the article and worked out the dosage used for the claimed effect?
Rocket
19 Feb 2017
New article on GHK from Dr. Pickart:
Brain Sci. 2017 Feb 15;7(2). pii: E20.
The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline.
Pickart L1, Vasquez-Soltero JM2, Margolina A3.
Research & Development Department, Skin Biology, WA 98006, USA
Neurodegeneration, the progressive death of neurons, loss of brain function, and cognitive decline is an increasing problem for senior populations. Its causes are poorly understood and therapies are largely ineffective. Neurons, with high energy and oxygen requirements, are especially vulnerable to detrimental factors, including age-related dysregulation of biochemical pathways caused by altered expression of multiple genes. GHK (glycyl-l-histidyl-l-lysine) is a human copper-binding peptide with biological actions that appear to counter aging-associated diseases and conditions. GHK, which declines with age, has health promoting effects on many tissues such as chondrocytes, liver cells and human fibroblasts, improves wound healing and tissue regeneration (skin, hair follicles, stomach and intestinal linings, boney tissue), increases collagen, decorin, angiogenesis, and nerve outgrowth, possesses anti-oxidant, anti-inflammatory, anti-pain and anti-anxiety effects, increases cellular stemness and the secretion of trophic factors by mesenchymal stem cells. Studies using the Broad Institute Connectivity Map show that GHK peptide modulates expression of multiple genes, resetting pathological gene expression patterns back to health. GHK has been recommended as a treatment for metastatic cancer, Chronic Obstructive Lung Disease, inflammation, acute lung injury, activating stem cells, pain, and anxiety. Here, we present GHK's effects on gene expression relevant to the nervous system health and function.
KEYWORDS:
Alzheimer’s disease; DNA repair; GHK; Parkinson’s disease; anti-anxiety; anti-oxidant; anti-pain; copper; dementia; glial cells; neurons
PMID: 28212278
Really? GHK does all that? Will it change the oil in my truck, or lower my taxes?
Anyone who wastes money on this product has been advised: it does NOTHING. You would have to look at my GHK log someplace here on Longecity.......... But I used it daily for at least 6 weeks at a significant dose. It does nothing. It did nothing. It will do nothing. If you want to a use a peptide that will heal the body, 1mg ED of BPC157 is absolutely fantastic. But be warned, not all BPC157's are equal. I have use 2 different sources: source A I can shoot up 1mg and the next day feel relief from soft tissue pain. Source B has no effect. If anyone wants to know my source of the REAL BPC157 just shoot me a PM.
I don't trust Dr. Pickart. It's funny, when I look on PubMed for GHK, I see Pickart's name on everything.
A fool and their money are soon parted. That's the last I will say.
Colorow
19 Feb 2017
In the meantime, the skin crazies (I am one) think topical GHK works ok, sorta well. However I ordered a few times and received a self promoting pseudoscience very thick book, free and unrequested. Every expensively published page basically said GHK fixes everything aging related. From the man selling skin cream. Is he selling injectable GHK now?
I do wish it were so easy.
Sent from my iPad using Tapatalk
Logic
23 Feb 2017
...Anyone who wastes money on this product has been advised: it does NOTHING. You would have to look at my GHK log someplace here on Longecity.......... But I used it daily for at least 6 weeks at a significant dose. It does nothing. It did nothing. It will do nothing....
...But be warned, not all BPC157's are equal. I have use 2 different sources: source A I can shoot up 1mg and the next day feel relief from soft tissue pain. Source B has no effect...
Keeping the 2nd statement above in mind; may I enquire as to your GHK source plz Rocket?
Also; were you taking GHK or GHK-Cu?
A mixture?
rb1
23 Feb 2017
Anybody looking for the best place to buy
GHK/GHK-cuhttp://teamtlr.com/a...atio-blend.html
The crew who run this outfit are extremely responsive to questions, and having reviewed many sites selling peptides , these guys take some beating.
Highly recommended.
dz93
23 Feb 2017
Anybody looking for the best place to buy GHK/GHK-cu
http://teamtlr.com/a...atio-blend.html
The crew who run this outfit are extremely responsive to questions, and having reviewed many sites selling peptides , these guys take some beating.
Highly recommended.
This account was literally just now created. I actually believe TLR to have been involved in some nefarious acts involving attacks on competing businesses. I can't confirm this, but based on events that took place during a group buy through TLR for GHK-Cu, its clear what happened. TLR essentially offered to supply GHK-Cu for a group buy, when another competing business had reasonably questioned the purity of said subsrance, TLR later proceeded to call various credit card processors, accusing the competing company of selling illegal substances for human use. Now, they competing company has suffered for simply warning the community to be cautious about ordering a substance from a company that doesn't even label the ingredients in their "private blends". Want to order mystery compounds and hope you get what you originally wanted? Order from TLR.
I will admit, during the group buy, I gave them the benefit of the doubt. Seeing the aftermath, I will never deal with them again. Take what you want from this, but do consider the fact that this account was literally created minutes ago and is now desperately advertising their GHK-Cu as if no one learned their lesson the first time.
Why not!
24 Feb 2017
Yep, DZ93, re. TLR, I totally agree with you. They are total fuckign dickheads of the highest order.
Though it's not just the integrity of their products and their practices and conduct, but their nonsensical woffle and BS they were spurting out in that thread section during the GHK Group buy saga.
I love how everyone thought/was under the impression it was a new synthesis, which was further supported by the fact it was taking TLR months to supply.
Then at the very end, after about 3 or 4 months, after TLR had been requested SEVERAL times to provide test reports (but they hadn't - yet any honest and professional supplier would have provided them in the first place without having to be asked by customers), when they finally provided the MS and HPLC reports, they were dated 2013 or 2014, years before!!!
They were in fact supplying GHK which was years old from stock, yet they conveniently failed to inform customers of this very important aspect. AND, it took them 3 or 4 months.
The 'years old stock' (not new synthesis as everyone assumed) was but one highlight of a show which was fantastic entertainment at the time.
Werper
24 Feb 2017
Bought some ADDX-OX from TLR, after a reading a post claiming how well it worked. ADD-OX didn't work for me, and I believe TLR to be a scam.
Rocket
01 Mar 2017
I thought we're not allowed to talk about suppliers here? But I have bought 2 items from TLR that were legitimate, and the most recent one being the D+Q product.
BieraK
02 Mar 2017
Why guys you don't try with Ceretropic?, Ceretropic sells quality peptides.
This user on reddit reported a very good response from GHK:Cu, looks very powerful
https://www.reddit.c...ays_into_ghkcu/
OK so GHK-Cu is weird. Yesterday I injected 2mg subQ, can't really say if I noticed much, but this morning I injected 4mg subQ and like all my inflammation disappeared. This 4mg was stronger than the highest ibuprofen dose I've ever taken regarding inflammation reduction. (like 1.2grams ibuprofen). About an hour later I worked out and I've had the strongest pump/soreness I've ever had regarding lifting. Also I'm in a ridiculously good mood and don't feel sluggish mentally (probably because of CNS inflammation reduction?)
I'm curious weather these effects will last after the full vial or if this is only while it's in my blood stream. Cause if it's only while it's in my blood stream I think that price tag isn't too bad cause I feel fan-fucking-tastic.
Edited by BieraK, 02 March 2017 - 08:38 PM.
DareDevil
03 Mar 2017
I thought we're not allowed to talk about suppliers here? But I have bought 2 items from TLR that were legitimate, and the most recent one being the D+Q product.
While I can't vouch for anything else they sell I can vouch that the D+Q from TLR is the real McCoy. I compare their effectiveness to the prescription Sprycel I tried a year ago and to the Quercetin I had sourced elsewhere before. I also found the Epitalon sourced at Ceretropic to be effective, although I didn't have any other point of comparison. Let's please not drift into a quarrel about suppliers especially when there are very different member experiences with them. Keeping it to the products versus their source is more constructive. Discussions about sources are best kept to PMs. DareDevil
DareDevil
03 Mar 2017
OK so GHK-Cu is weird. Yesterday I injected 2mg subQ, can't really say if I noticed much, but this morning I injected 4mg subQ and like all my inflammation disappeared. This 4mg was stronger than the highest ibuprofen dose I've ever taken regarding inflammation reduction. (like 1.2grams ibuprofen). About an hour later I worked out and I've had the strongest pump/soreness I've ever had regarding lifting. Also I'm in a ridiculously good mood and don't feel sluggish mentally (probably because of CNS inflammation reduction?)
I'm curious weather these effects will last after the full vial or if this is only while it's in my blood stream. Cause if it's only while it's in my blood stream I think that price tag isn't too bad cause I feel fan-fucking-tastic.
Hi BieraK,
From previous posts I had heard of a dosing protocol of 75mg subQ 3 times/week. This is far greater than the dosage stated above of only 4mg in a single injection. Are you sure this is sufficient for effective results? TIA. DareDevil
G-e-e
04 Mar 2017
Why guys you don't try with Ceretropic?, Ceretropic sells quality peptides.
This user on reddit reported a very good response from GHK:Cu, looks very powerful
https://www.reddit.c...ays_into_ghkcu/
OK so GHK-Cu is weird. Yesterday I injected 2mg subQ, can't really say if I noticed much, but this morning I injected 4mg subQ and like all my inflammation disappeared. This 4mg was stronger than the highest ibuprofen dose I've ever taken regarding inflammation reduction. (like 1.2grams ibuprofen). About an hour later I worked out and I've had the strongest pump/soreness I've ever had regarding lifting. Also I'm in a ridiculously good mood and don't feel sluggish mentally (probably because of CNS inflammation reduction?)
I'm curious weather these effects will last after the full vial or if this is only while it's in my blood stream. Cause if it's only while it's in my blood stream I think that price tag isn't too bad cause I feel fan-fucking-tastic.
I would totally order from Ceretropic. I have done so in the past and I find them to be more trustworthy than TeamLTR. But Ceretropic's prices on GHK-CU are out of touch. If they were to come down in price and be more competitive I would have no hesitation in switching over.
Does this forum have a shit list? If TeamLTR are providing questionable products and multiple sources can confirm, they should be blacklisted for the sake of community awareness.
Lots of people (like myself) visit this forum to learn about this stuff. Many of us have no scientific background whatsoever. It's concerning to me that 1 year on from the TeamLTR drama I'm still reading that people think the product isn't legitimate. I thought that was put to bed and it was confirmed as authentic during the team buy?
Can anyone please shed light on this.
For the sake of public safety I think it's importance this is addressed once and for all.
mikey
04 May 2017
Hi Longecity Friends,
This isn't out of laziness as I've read tons of threads about GHK here and elsewhere
But still can't find the answer to 2 questions I've been asking myself.
- Is GHK with copper dangerous or require super low doses?
The source I found with PAL GHK is expensive (unless doses are low):
https://www.peptides...ces.com/pal-ghk
- Is anyone organizing a Group Buy so that this can become cost effective?
Thanks for your help. I am not looking for a shortcut but need to be set straight on these two issues.
Cheers,
DareDevil
A year of so TLR gave us a group buy on a 1:1 mix of GHK and GKH-cu, which was arrived at as optimal after a round of chemical analysis by our experts.
(That's a long read back, but it's easier than me explaining it, A question that is answered is why having both GHK and GHK-cu (copper) is desirable.)
I thought that TLR's current price was OK and better than some others, whether group buy or not.
DareDevil
04 May 2017
Thanks Mikey!
I just placed an order for TLR's combo I hadn't noticed it was a blend and had no idea it was a formulation arrived at by contributors in the Longecity forums. It is less expensive than many I've seen. All I need to know now, is how to administer and at what doses? I expect daily Sub-Q injections and maybe also local injections where one wishes to heal injuries or regenerate the skin. Any ideas on what to combine GHK with are welcome.
Cheers,
DareDevil
Oakman
04 May 2017
There are (at least) three suppliers of GHK on Amazon. The first one says it's a DIY product meant to be mixed in your own creams or ointments. It sounds legit, they say they have used the same supplier for 5-7 yrs.
Search Amazon for "GHK", the product is called "Copper Peptide Solution GHK-Cu 15 ml fluid CP 100% Ingredient for DIY Rejuvenate Skin Hair Nails Cell Turnover"
DareDevil, you might want to look at the formulation on Amazon using GHK to get ideas for your own creation.
Rocket
05 May 2017
stolpioni
27 Sep 2017
I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
Was this from TLR? If so then no wonder.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
meatsauce
27 Sep 2017
I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
Was this from TLR? If so then no wonder.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
Where did you get your GHK-Cu? I thought the GHK from TLR was shown to be legit.
Rocket
28 Sep 2017
I bought from TLR. All I can say is that it looked exactly like real peptide from pics I have seen. Its an expensive waste of time. Stick to things that work such as bpc or cjc.Where did you get your GHK-Cu? I thought the GHK from TLR was shown to be legit.Was this from TLR? If so then no wonder.I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
Why is there only 1 person pushing this stuff? These quacks like this guy and that Ana Aslan and that junk she was pushing....
Edited by Rocket, 28 September 2017 - 01:05 AM.
stolpioni
29 Sep 2017
I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
Was this from TLR? If so then no wonder.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
Where did you get your GHK-Cu? I thought the GHK from TLR was shown to be legit.
I don't know whether this particular product was real, but if you look at this reddit thread you will see that most of the products they sell are complete bunk:
https://www.reddit.c...esting_results/
I bought mine from Ceretropic. I am not affiliated with them in any way but I think they are quite a trustworthy source in this sketchy business. I can tell you that I have an immediate effect when injecting their GHK-Cu. My body relaxes, my breathing gets easier, and overall I feel a reduction in inflammation. I know this because of a severe injury to my dick, which has made the color of it to be very dark red or dark brown. After injecting GHK-Cu, the color of it will turn much whiter and more normal looking.
stolpioni
29 Sep 2017
I bought from TLR. All I can say is that it looked exactly like real peptide from pics I have seen. Its an expensive waste of time. Stick to things that work such as bpc or cjc.
Where did you get your GHK-Cu? I thought the GHK from TLR was shown to be legit.
Was this from TLR? If so then no wonder.I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
Why is there only 1 person pushing this stuff? These quacks like this guy and that Ana Aslan and that junk she was pushing....
So it had a blue color? I think it'd be pretty easy to color any peptide blue if one wanted to. Most probably TLR are buying from China and we all know they got tricks up their sleeves to pull off scams.
I am not pushing anything, this is the first time I have ever posted in this thread. But elsewhere online you can read a lot of positive reports of GHK-Cu, where as here there are mostly negative reports. It seems plausible that you have injected bunk, that's all.
I have only used it for a couple of days, so I can't say whether it'll have any long term impact yet. But it for sure does something. It is more noticeable than BPC 157 so far (which I started using yesterday).
Edited by stolpioni, 29 September 2017 - 08:21 PM.
stefan_001
29 Sep 2017
I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
Was this from TLR? If so then no wonder.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
Where did you get your GHK-Cu? I thought the GHK from TLR was shown to be legit.
I don't know whether this particular product was real, but if you look at this reddit thread you will see that most of the products they sell are complete bunk:
https://www.reddit.c...esting_results/
I bought mine from Ceretropic. I am not affiliated with them in any way but I think they are quite a trustworthy source in this sketchy business. I can tell you that I have an immediate effect when injecting their GHK-Cu. My body relaxes, my breathing gets easier, and overall I feel a reduction in inflammation. I know this because of a severe injury to my dick, which has made the color of it to be very dark red or dark brown. After injecting GHK-Cu, the color of it will turn much whiter and more normal looking.
Uhh yeah thats convincing anecdotal evidence...
meatsauce
29 Sep 2017
I've used this peptide for at least 6 weeks. Total bust. Stick to things that work such as BPC157 (from reputable source) for real healing.
Was this from TLR? If so then no wonder.
I am using real GHK-Cu and I can feel an immediate anti-inflammatory effect that lasts for 1-2 hours after every 5mg injection.
Where did you get your GHK-Cu? I thought the GHK from TLR was shown to be legit.
I don't know whether this particular product was real, but if you look at this reddit thread you will see that most of the products they sell are complete bunk:
https://www.reddit.c...esting_results/
I bought mine from Ceretropic. I am not affiliated with them in any way but I think they are quite a trustworthy source in this sketchy business. I can tell you that I have an immediate effect when injecting their GHK-Cu. My body relaxes, my breathing gets easier, and overall I feel a reduction in inflammation. I know this because of a severe injury to my dick, which has made the color of it to be very dark red or dark brown. After injecting GHK-Cu, the color of it will turn much whiter and more normal looking.
Your dick dude! What the hell happened did you slam it in a door or get a little to rough with a girl!?
stolpioni
30 Sep 2017
Your dick dude! What the hell happened did you slam it in a door or get a little to rough with a girl!?
The second part unfortunately. Hasn't been the same for almost 9 months now :/.
Timshell
01 Oct 2017
Has anyone determined the proper injection amount/dosage for GHK-cu? We purchased a vial of GHK-cu 50 mg. and used the bacteriostatic water. Now, how much to inject, and how many injections per day? Thank you, Lois Rogers